Intro To Pharmacoeconomics Flashcards

1
Q

What is the Quadruple Aim of healthcare?

A
  1. Improving population health
  2. Reducing costs of care
  3. Enhancing patient experience
  4. Improving provider satisfaction
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the difference between “fee-for-service” and “pay-for-performance”?

A

Fee-for-service: incentive to provide MORE services, but high volume ≠ better quality of care

Pay-for-performance: incentive for providers to deliver high quality care at lower costs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Define pharmacoeconomics

A

Analysis of COSTS & CONSEQUENCES of pharmaceutics and its effects on patients/health systems/society

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What are the goals of pharmacoeconomics?

A
  • To identify, measure and compare costs vs outcomes of pharmaceutical interventions
  • To allocate health resources & that each patient gets the most suitable treatment

(Includes methods from statistics, clinical epidemiology, decision analysis, psychometrics)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is the main reason pharmacoeconomics has arisen as a necessary area of study?

A

Rising competition for limited/diminishing health resources has created the need to appraise utilization.
Note: cheapest alternative ≠ best option!

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is the ECHO model in pharmacoeconomics?

A

Economic - direct/indirect/intangible costs vs medical outcomes
Clinical - medical events that occur from disease
Humanistic - consequences of disease/treatment on QoL
…Outcomes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are direct medical costs? Provide examples

A

Costs from medical products/services for prevention, detection, and treatment.
Medication, supplies, labs, provider’s time, hospitalization

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are some direct non-medical costs?

A

Transportation, food, family care, home aids

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are some indirect costs?

A

Lost wages (from morbidity), lost costs from premature death (mortality)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Define incremental costs

A

Additional costs incurred from trying alternative treatment strategies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are intangible costs? Provide examples

A

Costs of pain, grief, inconvenience and other nonfinancial outcomes of disease and medical care.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are opportunity costs? Provide examples

A

Cost of forgoing the best alternative when making a choice between different options. TLDR: it represents the missed benefits that could have been obtained if resources (such as time, money, or effort) were used in an alternative way.
Ie. Missed opportunities, forgone revenue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Whose perspectives matter when assessing economic outcomes? (4) Which is considered the “best”?

A

Patient, provider, payer, society
Society considered “best”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is Cost of Illness (COI)? How is it applied?

A

Estimates the total costs of a disease on a population

(Used as a baseline to compare the value of various treatments against the cost of the illness)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is Cost-Minimization Analysis (CMI)? What is its application?

A

Find the least expensive cost alternative between therapeutically equivalent treatments

The least expensive agent is preferred [includes cost of drug preparation, administration and storage, etc]

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What is a Cost-Benefit Analysis (CBA)? What is its application?

A

Measures benefits of therapy in monetary units, computes a net gain
(Allows for comparison of programs with different objectives)
Ie. If treatment is $100 and value of treatment is $1000, then cost-benefit ratio is 1000/100 = 10/1

CONTROVERSIAL! Valuing of treatment with $ is subjective

17
Q

What is a Cost-Effective Analysis (CEA)? What is its application?

A

Compares treatments’ costs ($$) to outcomes in effectiveness/natural units (lives saves, cured pts, life expectancy, etc)
[Used to compare competing treatment alternatives that differ in therapeutic outcomes]
focus on cost optimization!

18
Q

What is an Average Cost Effectiveness Ratio (ACER)? What is an Incremental Cost Effectiveness (ICER)?

A

ACER is total healthcare costs vs clinical outcomes ($ vs effectiveness unit)
ICER is the additional cost of an add-on treatment vs the additional % increase in effectiveness
(ACER = cost per benefit of a new strategy independent of other alts.
ICER = cost per unit of benefit of switching from one treatment strategy in place to another.)

19
Q

What is Cost-Utility Analysis? What is its application?

A

Compares treatments with cost ($) and outcomes in terms of QoL or patient preference

Measured in QALYs (represents the number of full years at full health)

MOST useful for life-extending treatments with serious AEs (ie. Chemo), treatment reduces morbidity rather than mortality

20
Q

What is the focus of Humanistic Evaluation methods?

A

Health-related quality of life (HRQOL) including physical, emotional, social effects