Intro to pharm-Segars Flashcards
This field studies how the drug affects the body as well as the MOA-How drugs induce BCHEM and PHYS effects
Pharmacodynamics
This field studies how the body affects the drug-the time related PHYS process of moving the drug throughout the body
Pharmacokinetics
ADME
__ is a drug which resides in an inactive form (as manufactured) and when administered is transformed (metabolized) into an active compound
Pro-drug
List the components of Pharmaceutical Equivalence:
- Same ingredients
- Same dosage form/route
- Same strength and concen.
And meet the same standards for quality/purity
___ is the same drug but different salts/complexes, or different dosage forms or strengths
Pharmaceutical alternative
Describe Therapeutic equivalence
Must be pharmaceutically equivalent AND expected to have the same:
- Therapeutic (clinical) effect
- Safety profile
___ is similar rate and extent of absorption
Bioequivalence
Bioequivalence is ___ % of reference product
80-125
Which Scheduled/controlled drug class has no FDA-approved indications?
Class I
List the legal requirement of writing a prescription:
1) Name/address of prescriber
2) Name/address of patient
3) Date Rx was written (include year)
4) Name & strength of med
5) Directions for use (acceptable abbrevs. only)
6) Quantity to be dispensed (# and spelling)
7) # of refills allowed (# and spelling)
8) Prescribers signature ( 2 lines to choose from)
9) Prescribers DEA #
When writing a Rx, which components require the number and spelling?
- Quantity to be dispensed
- # of refills allowed
What is the life-span of a non-controlled legend?
12 months OR # of refills (whichever occurs 1st)
What is the life-span of a controlled/scheduled legend?
6 months OR # of refills (whichever occurs 1st)
What is the legal limit on # of refills for C3-C5?
What is the legal limit on # of refills for C2?
5 refills
Zero refills
What is the legal limit on quantity dispensed for C3-C5?
What is the legal limit on quantity dispensed for C2?
90 days
30 days
Partial filling of Rx is only allowed for which controlled/scheduled classes?
3-5 –> until full quantity of Rx and all refills dispensed or expiration (1 year)
Partial filling is not possible for C2 drugs unless:
-Pharmacist doesn’t have full quantity (72 hrs)
OR
-Long-term care/hospice
How is the term “Emergency” defined for a controlled agent?
- Immediate administration is necessary for proper tx of the intended ultimate user, or
- No appropriate (alternative) tx is available, including administration of a drug which is not a C2 substance, or
- It is not reasonably possible for prescriber to provide written Rx to the pharmacist prior to dispensing
how many lbs in a kg?
2.2
how many ml in a tsp?
5
how many ml in a tbsp.?
15 (or 3 tsps.)
how many ml in a quart?
946
2 pints=1 quart
how many ml in a pint?
473
16 oz=1 pint
how many L in a gallon?
3.79
4 quarts=1 gallon
