Intro To Nursing Exam 3 Flashcards
volume imbalances
- disturbances of the amount of fluid in the extracellular compartment
osmoality imbalances
- disturbances in the concentration of body fluids
hypernatremia
- water deficit
- hypertonic
- loss of relatively more water than salt or gain of more salt than water
hyponatremia
- water excess
- hypotonic
- arises from gain of more water than salt or loss of more salt than water
clinical dehydration
- extracellular volume deficit and hypernatrema combined
- ECV is too low and the body fluids are too concentrated
Nursing Management of fluid volume deficit
- measure all fluids that enter and leave the body
- check electrolytes, CBC, and urine-specific gravity
- assess for hypertension and weak pulses
- assess respiratory system and tissue perfusion
- check orientation, vision, hearing, relfexes, and muscle strength
- check for weight changes
- check for skin break down and good oral care
hypokalemia symptoms
- diarrhea, repeated vomiting
- use of potassium wasting diuretics
hyperkalemia symptoms
- decreased urine output
hypocalcemia symptoms
- acute pancreatitis, neuromuscular excitability
hypercalcemia symptoms
- commonly found in cancer patients
hypomagnesemia
- increases neuromuscular excitability
hypermagnesemia
- ESRD, neuromuscular excitability, lethargy, decreased deep tendon reflexes
pH
- reported degree of acidity
acid buffers
- are pairs of chemicals that work together to maintain normal pH of body fluids
respiratory acidosis
- arises from aveolar hypoventilation
- lungs unable to excrete enough CO2
- excess carbonic acid in the blood decreases pH
respiratory alkalosis
- arises from hyperventilation
- lungs excrete too much CO2
- deficit of carbonic acid in the blood increases pH
metabolic acidosis
- arises from increase in the metabolic acid or decrease in base (bicarbinate)
- kidneys unable to excrete enough metabolic acids which accumulate in the blood
- results in decreased level of conciousness
metabolic alkalosis
- arises from direct increase in base (bicarbonate) or decrease in metabolic acid
- results in increased blood bicarbonate
causes of alkalosis
- loss of gastric juices
- potassium wasting diuretics
- overuse of antiacids
- hyperventiliation
nursing process assessment
- nursing history, medical history, daily weights, fluid intake and output, labratory studies
nursing history
- age
- environment
- dietary intake
- lifestyle (alcohol intake, etc)
- medications
medical history
- recent surgery
- gastrointestinal output
- acute illness or trauma
- respiratory disorders
- burns
- trauma
- chronic illness
- cancer
- heart failure
- oliguric renal disease
daily weights
- indicator of fluid status
- use same conditions
fluid intake and output
- 24 hours I&O (compare intake versus output
- intake includes all liquids eaten, drank, or through IV
- output is urine, diarrhea, vomitus, gastric suction, wound drainage
isotonic solution
- have the same effective osmoality as body fluids
hypotonic solution
- have an effective osmoality less than bosy fluids, thus decreasing osmoality by diluting body fluid and moving water into cells
hypertonic solution
- have an effective osmoality greater than body fluids
IV equipment
- vascular access devices, tourniquets, clean gloves, dressings, IV fluid contains, various types of tubing, electronic fluid devices, infusion pumps
initiating IV therapy
- changing intravenous fluid containers, tubings, and dressings
- assissting patient with self-care activities
- complications: fluid overload, infiltration, extravasation, phlebitis, local infection, bleeding at the infusion sight, bruising
blood component therapy
- IV administration of whole blood or blood component
blood types
- O positive, O negative, A positive, A negative, B positive, B negative, AB positive, AB negative
Blood groups
A, B, AB, O
Autologous blood transfusion
- designates the reinfusion of blood or blood components to the same individual from whom they were taken
pure food and drug act
- medication free from impurities
FDA
- rigorous testing on potential products
medwatch program 1993
- HCP report when harm done
ISMP
- help health care practitioners understand medication error from a systems perspective, collect reports of errors, and disseminate recommendations to help prevent similar occurrences
drug
- any substance that alters physiologic function with the potential of affecting health
medication
- a substance used in the diagnosis, treatment, cure, relief, or prevention of health alteration
- regulated by the FDA
drug administration purposes
- diagnostic, prophylaxis, therapeutic
drug diagnostic purpose
- assessment of liver function
- diagnosis of myasthenia gravis
drug prophylaxis purpose
- heparin to prevent thrombosis
- antibiotics to prevent infection
drug therapeutic purpose
- replacement of fluids or vitamins
- supportive purposes (to enable other treatments such as anesthesia)
- palliation of pain and sure
chemical drug names
- various chemical compounds
generic drug names
- manufacturer who develops, helps to recognize class
trade names
- first manufacturer of drug
classfication of drugs
- based on its desired effect on the body system
medication forms
- solid, liquid, topical, parenteral, sterile for body cavity instillation
medication actions therapeutic effect
- expected and predicted response on body system
side effects
- unintended and nontherapeutic effects which can range from tolerable to harmful and sometimes irreversible damage or death
idiosyncratic reactions
- opposite or different response than expected such as hyperactivity with Benadryl
synergistic effect
- 2 drugs cause greater body response when given together (positive or negative)
allergic reaction
- sensitized immune response, unpredicted, simple itching, hives, rash, rhinitis
anaphylactic allergic reaction
- amergency ABC problems, treatment for bronchospasm, wheezing, edema
skin rash
- small, raised vesicles that are usually reddened
- often distributed over entire body
pruritus
- itching of the skin with or without rasha
angioedema
- edema due to increased permeability of blood capillaries
rhinits
- inflammation of mucous membrances lining nose
- causes swelling and clear, watery discharge
pharmacokinetics
- how medications enter and exit the body
- are absorbed and distributed
- reach their site of action
- alter body processess and are metabolized
absorption pharmacokinetics
- passage of medication molecules into the blood from the site of administration
- factors that influence: route of admin, ability of medication to dissolve, blood flow to site of admin, body surface area, lipid solubility
distribution pharmacokinetics
- occurs after absorption within the body to tissues, organs, and specific sites of action
- depends on physical and chemical properties of medication, physiology of the person taking it, circulation, membrane permeability, protein binding
metabolism pharmacokinetics
- medications are metabolized into a less-potent or an inactive form
- biotransformation occurs under the influence of enzymes that detoxify, break down, and remove active chemicals
- most biotransformation occurs in the lover
- kidneys, blood, intestines, and lungs play a role
excretion pharmacokinetics
- medications exit the body through kidney (urine), liver (bile), bowel (stool), lungs (gases), exocrine glands (lipid, soluable meds)
- chemical makeup of medication determines the organ of excretion
first pass effect
- phenomenon of drug metabolism at a specific location in the body which leads to a reduction in the concentration of the active drug before it reaches the site of action or systemic circulation
therapeutic range
- constant blood level between MEC and toxicity
MEC
- want of a constant blood level
peak
- considered the maximal therapeutic level, mex serum dose, time varies
trough/level
- the lowest therapeutic level
- can be measured by a lab draw just prior to the next scheduled dose
onset
- body response to medication
duration
- therapeutic range of medication
biological half-life
- the time it takes for excretion to lower the blood concentration of a drug to decrease by 50%
- determines how often medication is given
plateau
- occurs when a medication blood serum concentration reaches therapeutic effect and remains there
time-critical medications
- 30 minutes before or after scheduled time
- non-time critical (within 1 hour of time due)
patient teaching
- nurse tells how patient when and how to take medications
essential parts of drug order
- full name of patient and file
- date and time order is written
- name and dosage of drug
- route of drug admin
- rfrequency of drug admin
- signature and stamp of health care provider
- if over the phone must RBAV - read back and verify
medication rights
- patient, medication, dose, time, route, documentation
standing or routine medication admin
- administered until the dosage is changed or another medication is prescribed
single medication
- given one time only for a specific reason
now medication
- when a medication is needed right away but not STAT
prn medication
- medication given when the patient requires it
STAT medication
- given immediately in an emergency
prescription medication
- medicatio to be taken outside of the hospital
assessment for medication
- always assess patient after giving medications that affect RR, HR, BP, LOC, blood sugar, and pain
onset times for medication
- IV: 3-5 min
- IM: 3-20min
- SC: 3-20min
- PO: 30-45min
medication reconciliation
- goal is to develop, update, coordinate, and comminucate accurate client medication information during transitions of care
polypharmacy
- increase risk of adverse reactions and interactions
- 5 or more meds on a nonhospitalized client
- meds with same actions or chemical class
- risk of drug-drug or drug-food interactions
- taking herbal or nutritional supplements
- OTC meds
- multiple pharmacies or providers
routes of administration
- oral, sublingual, buccal, inhalation, parenteral, intravenous, intramuscular, intradermal, subcutaneous, topical
topical medication admin
- medications applied to the skin and mucous membranes generally have local effects
- applied to skin
- rectal
- vaginal
- otic
- optic
- nasal
oral administration
- easiest and most desirable route
- empty stomach (1 hr before or 2 hr after)
- risk of drug-drug interaction is higher
- do not crush sustained release or enteric coated medications