Intro To NS

Question 1

Cells with most dendritic branches?

Answer 1

Purkinje cells of cerebellum

Question 2

Synapses preferentially made on:

A. Dendrites
B. Dendritic spines
C. Axonal spines
D. Axons

Answer 2

B. Dendritic spines

Question 3

Neuronal cilia location?

A. Axons
B. Dendrites
C. Cell body
D. Nucleus

Answer 3

C. Cell body

Question 4

Na+ channels highly localized to which region?

A. Axon hillock
B. Dendrites
C. Dendritic spines
D. Axon

Answer 4

A. Axon hillock

Question 5

Repeating segments of localized density of Na+ channels

Used to increase conduction down an axon

Used to regenerate action all potentials

AP often jumps over these

Answer 5

Nodes of Ranvier

Question 6

1. Most common synapse type
2. Least common synapse type
3. Common GABAergic synapse

Answer 6

1. Axo-dendritic
2. Axo-axonic
3. Axo-somatic

Question 7

A patient is found to have a condition where the contacts with cerebral blood vessels are affected and patient shows defective glutamate and K+ uptake at the blood-brain barrier. Which type of glial cell is most likely defective?

A. Microglia
B. Oligodendrocytes
C. Schwann cells
D. Astrocytes

Answer 7

D. Astrocytes

Question 8

Patient presents with Alexander disease, characterized as a mutation glial-fibrillary acidic protein that impairs patients ability to form a barrier, confine a lesion, and prevent the spreading of CNS damage. Which cell is likely defective?

A. Microglia
B. Oligodendrocytes
C. Schwann cells
D. Astrocytes

Answer 8

D. Astrocytes

Question 9

Patient presents with defective immune responses in the nervous system. Defective phagocytosis and inflammation is observed. Which cell is likely defective?

A. Microglia
B. Oligodendrocytes
C. Schwann cells
D. Astrocytes

Answer 9

A. Microglia

Question 10

Patient presents with muscle weakness. The physician suspects a deficiency of myelin. Which is most likely defective?

A. Microglia
B. Oligodendrocytes
C. Schwann cells
D. Astrocytes
E. A and c
F. B and C

Answer 10

F. B and C

Question 11

Patient presents with disruption of CSF flow in the ventricular system due to damaged cilia of which of the following cells?

A. Glial cells
B. Ependymal cells
C. Schwann cells
D. Pericytes

Answer 11

B. Ependymal cells

Question 12

Patient presents with low concentration of CSF. Which of the following cells are most likely affected?

A. Ependymal cells of ventricle
B. Pericytes
C. Choroid plexus cells
D. Neuronal plexus cells

Answer 12

C. Choroid plexus cells

Question 13

Cells that wrap around vessels and have been observed to participate in phagocytosis, macrophagic activity, and vasomotion.

Answer 13

Pericytes