intro to immunology

Question 1

components of innate immunity

Answer 1

microbes
epithelial barriers
complements
phagocytes
NK cells

Question 2

components of adaptive immunity

Answer 2

B lymphocytes
antibodies
T lymphocytes
effector t cells

Question 3

innate vs adaptive immunity interms of 
development
fast/slow
short/long duration
specificity 
memory

Answer 3

innate: present at birth, fast, short, low specificity, no memory,
adaptive: increase with exposure/slow/long/high specificity/memory

Question 4

molecules of innate vs adaptive immunity

Answer 4

innate: defensins/complement/chemokines/cytokines
adaptive: antibodies/t cell receptor/cytokines/chemokines

Question 5

what are defensins made of? what do they do? what are they produced by? where are they found?

Answer 5

anti-microbial peptides
disrupt microbial cm
produced by epithelial and immune cells
skin/mucosa/breast milk

Question 6

what do complements do

Answer 6

enzymes that are involved in opsinisation-> helps antibodies and phagocytes clear microbes and damaged cells

Question 7

what are chemokines

Answer 7

small molecules
attract cells along a gradient to sites of inflammation
separates lymphocytes into zones

Question 8

what are cytokines

Answer 8

made by cells to modify/suppress/activate cells in an autocrine/paracrine fashion
eg interferons/interleukins

Question 9

what do T cells do

Answer 9

bind to specific antigens on pathogens-> ligation-> activation