Intro to Genomics

Question 1

What is Genomics?

Answer 1

Study of the entire DNA sequence that contains the complete set of genes for an organism

Question 2

What is Genetics?

Answer 2

Study of how traits are passed down the generations and the role of genes in that process

Question 3

What is the Transcriptome?

Answer 3

DNA is transcribed to RNA and the total RNA content produced is the transcriptome

Question 4

What is the Proteome?

Answer 4

RNA is translated into protein and the total protein content produced is the proteome

Question 5

What is transcriptomics?

Answer 5

Study of all RNA transcripts produced by a cell, tissue or organism

Question 6

What is the significance of the Proteome?

Answer 6

This is the source of an additional level of variation

Question 7

How does the proteome create variation?

Answer 7

Proteins have different patterns of carbohydrates added on post-translationally

Question 8

How big is the mitochondrial genome?

Answer 8

16kbp

Question 9

What can a varying mitochondrial genome cause?

Answer 9

Many diseases associated with variants

Question 10

How does the epigenome vary?

Answer 10

Changes in marks on the DNA strand or in histones

Some disease associations

Question 11

What is the Metagenome?

Answer 11

Genomes of all the organisms from a specific location