Intro to Differential Diagnosis Flashcards

1
Q

*Describe the diagnosis processes

A

1) Pattern recognition
2) Hypothetico deductive
- Hypothesis generation
3) Algorithm
4) Exhaustive
5) Logical reasoning

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2
Q

*Components of illness scripts

A
  • Pathophysiology: what causes the disease
  • Epidemiology: who commonly gets this disease
  • Time course: how long it’s been going on
  • Symptoms & signs
  • Diagnosis: results of testing
  • Treatment: how would you treat this disease
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3
Q

*Differences between diagnosis informed care and medical screening

A

Diagnosis: uses directed questions & focused physical examination tests in a hypothesis-driven manner
Medical Screening: general systems review with the goal to assess for risk factors that may impact patients’ overall well-being

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4
Q

*Classification system of red flag screening

A

I = suggests serious pathology outside of MSK disorder, possible immediate intervention by a specialist
II =further patient questioning & adoption of selected examination methods
III = common, require further physical examination, likely to alter treatment

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5
Q

*Procedures to improve diagnostic accuracy (possible causes)

A
  • TIM VaDeTuCoNe
  • Trauma
  • Inflammation: aseptic or septic
  • Metabolic condition
  • Vascular: arterial, venous, or lymphatic
  • Degenerative
  • Tumor: malignant primary, malignant metastatic, or benign
  • Congenital
  • Neurogenic/Psychogenic
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6
Q

Examples of a medical diagnosis

A
  • stroke
  • fracture
  • foot pain
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7
Q

Examples of a PT diagnosis

A
  • impaired gait
  • generalized weakness
  • decreased force production
  • impaired AROM
  • pain
  • decreased strength
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8
Q

What is a diagnosis

A
  • Process + product of a clinical investigation related to the pathology underlying a patient/client’s signs & symptoms resulting in a label
  • investigation + label = diagnosis
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9
Q

What are some goals of a diagnosis

A
  • (Primary) determine whether PT services are indicated for the patient’s condition
  • identify the target disorder
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10
Q

Diagnosis limitations

A
  • cause of condition may not be determined
  • label may not be descriptive
  • specificity of labeling depends on information & experience
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11
Q

4 possible options for is the suspected diagnosis within scope of practice

A
  • Emergency referral: as a guide, on the same day
  • Urgent referral: as a guide, within 5 days
  • Watchful waiting: close surveillance while undergoing tx as required while allowing time to pass before medical intervention “treat and refer”, safety netting
  • Appropriate referral: diagnosis is within scope of practice, evaluate and treat
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12
Q

Define safety netting

A
  • management strategy used for people who may present with possible serious pathology
  • strategies should include advice on which signs & symptoms to look out for, which action to take, & the time frame within which that action needs to be taken
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13
Q

*Describe performing diagnosis informed care

A
  • PT interprets the diagnosis to determine appropriate intervention & prognosis
  • MUST prioritize the most important aspects of disablement to address in pain
  • most interventions have an indirect effect on pathology
  • requires PT to determine cause/effect between pathology & functioning
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14
Q

Limitations of diagnosis informed care

A
  • the label alone is insufficient to guide PTs
  • most PT referrals indicate: shoulder, knee, hip, back pain
  • essentialist approach relates to mechanism
  • “treat the patient, not the diagnosis!”
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15
Q

Define essentialism

A
  • treatment of the cause/source is more effective than treating individual signs & symptoms
  • mechanism is not always directly responsible for impairment in functioning
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16
Q

Where to start in thinking about a diagnosis

A
  • Formal processes decrease error
  • Start with the question: What disease is causing my patient/client’s dysfunction?
17
Q

Define backward and forward reasoning

A
  • Backward: make hypothesis and test it (novice)
  • Forward: pattern recognition (expert)
18
Q

Common age pattern for biceps tendonitis

A
  • common in 18-35 y/o involved in sports
19
Q

Pattern recognition foundations

A
  • Frequency: how common is the condition in that age group
  • Variability: inferences about entire population based on small subset patients
  • Causation: whether the person has a disease or not
  • Prototype: comparing a disease found in one patient to another with similar characteristics
  • Location: remote (referred) or local (palpation/over anatomy)
20
Q

Types of follow up questions to help differentiate/eliminate as many diseases as possible

A
  • Key feature: specific to a disorder & not others
  • Rejecting feature: if present then it is not the disorder & probably something else
  • Non-differentiating feature: common to several disorders (narrowing of possibilities)
  • Differentiating feature: specific to one or two disorders (further narrowing of possibilities)
21
Q

Difference between medical screening and red flag screening

A

Medical: involves an algorithmic process of systems based health review and focuses on the search for “Red Flags”
Red Flags: lack diagnostic accuracy to predict intended conditions and interpretation is often context-dependent requiring a deeper level of processing

22
Q

Red flags cluster for malignancy

A
  • > 50 y/o
  • failure of conservative management
  • unexplained weight loss
  • history of cancer
  • sensitivity of 100% for identifying a malignancy
23
Q

Examples of immediate medical attention (I) red flags

A
  • blood in sputum (coughed up substance)
  • loss of consciousness/altered mental status
  • neurological deficit not explained by monoradiculopathy
  • bowel/bladder changes
  • patterns of symptoms not compatible with mechanical pain
  • pulsatile abdominal masses
24
Q

Examples of require further physical tests & differential analysis (II) red flags

A
  • abnormal reflexes
  • bilateral or unilateral radiculopathy/paresthesia
  • unexplained referred pain
  • unexplained significant upper/lower limb weakness
25
Q

Examples of subjective questioning/examination procedures (III) red flags

A
  • > 50 y/o, clonus, fever, elevated ESR, gait deficit
  • Hx of disorder with infection/hemorrhage
  • Hx of metabolic bone disorder
  • Hx of cancer
  • impairment precipitated by recent trauma
  • long term corticosteroid use
  • long term workers compensation
  • non-healing wounds/sores
  • recent unexplained weight loss
  • writhing pain
26
Q

Diagnostic process for differential diagnosis/imaging

A
  • Identify patient’s chief concern & determine any communication barriers
  • Identify any red flags through medical screening
  • Create a sign/symptom timeline & appreciate anatomy
  • Create diagnostic hypotheses considering all possible forms of remote & local pathology
  • Ask specific questions to rule specific conditions as less likely
  • Perform tests to differentiate among remaining diagnostic hypotheses
  • Decide on a diagnostic impression
  • Determine appropriate plan of care (referral types)
27
Q

Risk factors for cardiovascular issues

A
  • (+)Age: men ≥45, women ≥55
  • (+)Family Hx: MI, coronary revascularization, or sudden death <55 in father or <65 in mother
  • (+)Cigarette Smoking: current smoker or quit within previous 6 mo
  • (+)Sedentary Lifestyle: <30 min of moderate intensity exercise at least 3 days per week for at least 3 mo
  • (+)Obesity: BMI ≥30 or waist >102 cm/40 in for men, waist >88 cm/35 in for women
  • (+)Dyslipidemia: LDL ≥130 or HDL <40, total >200
  • (+)Pre-diabetes: fasting glucose ≥100 but <126, 2 hr oral test ≥140 but <200
  • (-)High HDL Cholesterol: ≥60