Intro To Derm Flashcards
Average adult surface area
3000 in2
Varies in thickness from ___ to ___
.5 to 3 mm
Functions
- Protect against infection, desiccation, harmful light rays
- Maintain body temperature
- Receives stimuli from environment
- Stores chemical compounds
- Excretes waste products
- Synthesizes vit. D
Epidermis
4 layers (except 5 layers in soles and palms)
Deepest layers of the Epidermis
2 deepest layers- Stratum basale and Stratum spinosum
What forms during the process of degeneration?
Keratin (a waterproofing protein)
Outermost layer of the epidermis is?
Stratum corneum- 25-30 rows of flat dead cells that are filled with keratin and are shed and replaced continuously
Complete turnover of epidermis occurs?
28-30 days
Epidermal cells
Keratinocytes
Keratinocytes are bound by what?
intracellular junctions called desmosomes (vital for skin integrity)
Which two cells serve as protective functions in the epidermis?
Melanocytes and Langerhans cells
The dermis contains…
blood vessels, nerves, glands, and hair follicles
Upper layer of dermis
loose connective tissue
Deeper layer of dermis
netlike collagenous fibers that branch through subcutaneous tissue and attach to underlying bones and muscles
What are appendages of the skin?
Structures that develop from embryonic epidermis including hair, glands, and nails
Hair that’s soft and covers the body
vellus
Coarse hairs that develop at puberty, plus hairs of scalp and eyebrows
terminal hairs
External portion (outside the skin)
hair shaft
Internal portion (inside the skin)
hair root
Surrounding the root
Hair follicle (epidermis dipping down into the dermis to surround the root)
What are associated with the hair follicle?
Sebaceous glands, arrector pili muscles, and root hair plexuses *sometimes apocrine sweat gland
Color is a combination of what?
3 pigments (brown, black, theo melanin)
Graying?
Loss of pigment
Sebaceous glands
secrete sebum, at the hair follicle which protects the hair and skin from becoming too dry
Two types of sweat(sudoriferous) glands
Apocrine and Eccrine
Which glands begin at puberty?
Apocrine sweat glands located in axilla, pubic region, and breast areolae
Eccrine glands
Distributed throughout the skin
Parts of the nail
free edge, nail body, nail root, lunula (white area), cuticle (epidermis around the nail), nail bed (epidermis under the nail)
Skin color?
determined by melanin and carotene and by blood in the capillaries of the dermis
All races have…
same number of melanocytes but the amount of melanin produced varies
Increased melanin production is caused by
UV radiation increasing enzymatic activity
Carotene
pigment found in people of central and east Asian descent, adds yellowish hue to their skin
Epidermal ridges
genetically determined, unique for each individual, does not change throughout life except to enlarge, increase friction
Lines of cleavage/Langer’s lines/ skin tension lines
Collagenous fibers in dermis tend to run more in one direction, predominant direction is called Langer’s lines etc. (an incision made across the lines of cleavage ends to heal with broad, thick scar)
HPI
History of present illness
Dermatology HPI
taken before the physical exam is done, this is an exception. Doing the physical exam at the same time as taking the history can be more productive