Intro to Blocks/Segna Flashcards
full onset of nerve blocks may not occur for
30 minutes
benefits of blocks
- fast pain relief
- decreased risk of intraoperative bleeding, stroke, MI
- decreased intraoperative need for narcotics = less N/V, less constipation, faster wake up, discharge
- minimal risk - (dont get resp. depression) compared to tradiational pain managemnet
- may be able to avoid general anesthesia for certain cases (do entire cases under block)
rate of absorption in LAs
rate of absoprtion in LAs
- depends on vascularity
- increased vascularity will lead to faster systemic absorption, higher blood levels, shorter time to obtain peak levels,
- also greater risk for toxicity
Intravenous > Tracheal > intercostal > caudal > epidural > brachial plexus > sciatic > subq
Patients with hypoalbuminemia
are at a higher risk of LAST because LAs have a high degree of protein binding and the increased free fraction of the drug will predispose them to LAST
Clearance of LA is affected by
- shorter half life
- lower protein binding - more free drug
elimination rate dependent on concentration of free fraction
systemic toxicity
time and dose dependent
- more likely with higher serum levels/faster onset
- main. targets = CNS/ heart
true allergy to LA
is extremely rare
- esters -> PABA, cross rxn within group
- amides -> may contain methylparaben.
- no cross sensitivity between esters and amides
- epinephrine often MISTAKE as allergy
- patient should be fully monitored during entire block and at least 15 min after
Clinical Symptoms of LAST (Neuro)
- Early:
Circumoral numbness, dizziness, tinnitus, blurred vision
- restlessness, agitation, nervousness, seizures
- CNS depression: slurred speech, drowsiness, unconsciousness
- may bypass earlier symptoms with arterial (esp. vertebral) injections -> seizures
Clinical Symptoms of LAST (cards)
- LA-induced dysrhythmias: sodium channel blocking effect of LA
- prolongatoin of impulse conduction may lead to malignant arrhythmias
- lidocaine: less toxic bc fast in/fast out
- bupivacaine: more potent and toxic, fast in/slow out
treatment for LAST
- supportive (correct hypoxemia/acisosis)
- ACLS protocol - avoid lidocaine
- Intralipid:
- 20% emulsion
- 1.5mL/kg as initial bolus
- 0.25 mL/kg/min for 30-60 min
- bolus can be repeated 1-2 times for persistent asystole.
Commonly used block anesthetics and DOA
- ropivacaine: 12 hrs (pushed to 24 with adjuncts)
- bupiviaine: 15 hrs ~ 24 hrs
- lidocaine: 2 hrs
- mepivacine: 6 hours
supraclavicular block WITH neurostimulation has
a much higher rate of pneumothorax (5%) compared to other UE blocks
COPD is relatively contraindicaiton for
supraclavicular block because pleural apex may be higher
axillary nerve block has a high rate of failure for
single nerve injections
single injection ulnar block
block at elbow