Intro to Autonomic Pharmacology

Question 1

central nervous system

Answer 1

• brain

- spinal cord

Question 2

peripheral nervous system

Answer 2

-anything outside CNS

Question 3

peripheral nervous system is divided into ____

Answer 3

• autonomic nervous system

- somatic nervous system

Question 4

autonomic nervous system

Answer 4

controls cardiac and smooth muscle contraction as well as glandular secretion

Question 5

autonomic nervous system is divided into ____

Answer 5

• sympathetic nervous system

- parasympathetic nervous system

Question 6

somatic nervous system

Answer 6

• supplies skeletal muscle during voluntary movement

- conducts sensory information (pain and touch)

Question 7

peripheral nervous system is highly _____

Answer 7

integrated in the brain

Question 8

peripheral nervous system can influence processes _____

Answer 8

in distant regions of the body

Question 9

peripheral nervous system uses ____ feedback

Answer 9

negative

Question 10

transmission of information occurs with ____

Answer 10

chemicals (neurotransmitters)

Question 11

output of both sympathetic and parasympathetic divisions originates in the _____

Answer 11

brain and spinal cord; independent of each other

Question 12

both sympathetic and parasympathetic divisions are ____ systems

Answer 12

ganglionated

Question 13

parasympathetic preganglionic axons leave the CNS through the _____; ganglia are ____ the cells receiving input

Answer 13

cranial nerves and sacral spinal nerve roots;

close to

Question 14

sympathetic preganglionic axons leave the CNS thorugh the ______; ganglia are _____ the cells receiving input

Answer 14

thoracic and lumbar spine nerves;

far away from

Question 15

sympathetic distribution

Answer 15

wide

Question 16

parasympathetic distribution

Answer 16

limited

Question 17

sympathetic type of response

Answer 17

diffuse

Question 18

parasympathetic type of response

Answer 18

discrete

Question 19

somatic nervous system is a _____ system;
cell body in the ____;
axon extends to _____

Answer 19

non-ganglionated;
spinal cord;
skeletal muscle that it innervates

Question 20

synapse between somatic neuron and skeletal muscle is called the _____

Answer 20

neuromuscular junction (NMJ)

Question 21

cells innervated by a motor neuron or postganglionic neuron are called _____

Answer 21

effector cells

Question 22

there are some cells that possess receptors for ANS or somatic neurotransmitters but are not innervated by neurons; instead, they _____

Answer 22

respond to neurotransmitter released in blood stream

Question 23

sympathetic ganglion receptor

Answer 23

nicotinic

Question 24

parasympathetic ganglion receptor

Answer 24

nicotinic

Question 25

sympathetic effector receptor

Answer 25

adrenergic

Question 26

parasympathetic effector receptor

Answer 26

muscarinic

Question 27

NMJ receptor

Answer 27

nicotinic

Question 28

the ANS does not simply _____ the effector cells, rather it _____ activity (this is different than somatic system!)

Answer 28

stop and start;

modulates (increases or decreases)

Question 29

basal activity of pre and postganglionic neurons is ____; generation of action potential occurs ____

Answer 29

non-zero;

in the absences of input from CNS or preganglionic neurons

Question 30

autonomic nerves often classified based on primary neurotransmitter:
-acetylcholine: _____

Answer 30

cholinergic fibers

Question 31

autonomic nerves often classified based on primary neurotransmitter:
-norepinephrine

Answer 31

adrenergic fibers

Question 32

features of neurotransmitter function provide targets for therapy

Answer 32

• synthesis
• storage
• release
• effect
• termination of action