Intro of Pharmcology Flashcards
Pharmaceutic Phase
Pill disintegrates into particles dissolution prep for GI tract to the blood stream
Pharmacokinetic Phase
Delivery/Removal
Absorption GI to blood stream
Distribution delivery to site of action (may be affected by half life of the drug size)
Metabolism bio transformation inactivation elimination kidney removal from the body changes in kidneys can reduce causing acumalation of drug cause toxic
First Pass Effect
Liver metabolism inactivates a % of the active drug result needs higher dose than IV all blood leaving the GI tract leads to the liver
Pharmacodynamics
Study of drug concentration / resultant to effect of drug to body primary effect secondary effect side effect adverse effect toxic effect
Drug Incompability
Appears when there is a chemical reaction between two or more drugs
Agonist Drug
Antagonist Drug
Agonsit Drug Do more of something
Antagonist Drug Do less of something
Local Action
Systemic Action
Local Action ex creams ointments eye drops ears drops
Systemic Action delivered to intended site via the blood stream via GI tract (most common route)
The role of the RN in the nursing process
Teaching is to educate the patient watch for side effects adverse effects safety
Categories of scheduled drugs
Schedule 1 highest risk for abuse always be culturally aware of patient practices
Digoxin
Anything greater 2.5 brachycardia and hypertension
Additive Drug
Sum of two drugs that are administered together to increase a specific effect Ex diuretic
Synergistic Drug
Tylenol and Codeine be sure to watch when giving to post op pts
Antagonistic Effect
Two drugs given together have opposite mechanisms end canceling each other out ex Morpine overdose Narcan is given to reverse effects
Drug Food Interaction
Preg mom and kids no tetracyclines no dairy products
Decrease binding effects MAOI drugs no thymamine rich foods
Define Pharmocology
The study of drugs that alter functions of living organism
