Intro Flashcards
initial filtering component, ultra filtrate of plasma
renal corpuscle
Loop of Henle function
Main function: create concentration gradient in the medulla
main function of PCT
reabsorption
the DCT is under
hormonal control (PTH/aldosterone)
descending loop
water resorption
ascending loop
ions (NaCl)
Contain intercalated cells
Responsible for acid/base homeostasis
connecting/collecting duct
alpha cells secrete
beta cells secrete
Alpha: secrete (acid H+), reabsorb bicarbonate (HCO3-)
Beta: secrete bicarbarbonate, reabsorb H+
Regulates functions of each nephron, renal blood flow and GFR
Juxtaglomerular apparatus
granular cells secrete
renin
monitor NaCl concentration and adjusts GFR accordingly
macula densa
RAAS
a. Renin (kidney) + Angiotensinogen (liver) = Angiotensin I
b. Angiotensin I + ACE (lungs)= Angiotensin II
C. Angiotensin II is a potent vasoconstrictor, and causes release of aldosterone causing Na and H20 retention
Useful guide to determine overall kidney function- patients with kidney disease can still have normal
GFR= (urine concentration x urine flow)/ plasma concentration
Normal: 120 ml/min (male) and 100 ml/min (female) (150-250 L/24 hours)
( ) helps concentrate urine
medulla, loop of henle
KUB is used for
bowel pathology