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Cardiovascular > Intro > Flashcards

Intro Flashcards

1
Q

What three things affect diffusion?

A

Area available; resistance/permeability; concentration gradient

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2
Q

What is Fick’s Law?

A

J = PA(Ci - Co)

Where: J = rate of transfer; P = permeability; A = area; and Ci - Co = Concentration gradient

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3
Q

What is the hydrostatic pressure at the arteriolar end and the venular end?

A

~35mmHg and ~15mmHg

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4
Q

What is the coloid osmotic pressure?

A

25mmHg

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5
Q

What is the net result of ‘Starling Forces’?

A

Filtration at the arteriolar end forming approx 20 litres of interstitial fluid; and reabsorption at the venular end (approx 17 litres back into plasma)

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6
Q

Describe the metabolic needs of the brain

A

Constant - can be met by a flow of 0.5ml/min/g.

Extrememly intollerant to flow interuption.

Min = 750mls; Max = 750mls

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7
Q

Describe the metabolic needs of the heart

A

At rest it needs 0.9ml/min/g. If it has to work hard, its requierment increases four fold.

Extremely intollerant to inadequate flow.

Min = 300ml; Max = 1200ml

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8
Q

Describe the metabolic needs of the kidney

A

Requires constant high blood flow, though most flow is not nutitive. Flow can be moderated by need to defend composition of the fluid compartments of the body.

Min + Max = 1200ml

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9
Q

Describe the metabolic needs of the gut (and liver)

A

Gut and liver are connected in series via the hepatic portal system. At rest recieves 1ml/min/g. Digestion of a meal generates substantial increase in flow.

Can tolerate short term flow reduction.

Min = 1400ml; Max = 2400ml

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10
Q

Describe the metabolic needs of the skeletal muscles

A

Metabolic needs varies enormously. At rest flow needs to be 0.03ml/min/g, increasing to 6ml/min/g in exercise, but this may not meet metabolic needs.

Can survive a degree of anaerobic metabolism.

Min = 1000ml; Max = 16000ml

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11
Q

Describe the metabolic needs of the skin

A

Not very metabolically active. May be supported by 0.03ml/min/g, which may increase to 0.1ml/min/g for thermoregulation.

Min = 150ml; Max = 500ml

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12
Q

Describe the metabolic needs of the rest of the body

A

Fairly constant overall demand.

Min/max = 200ml

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13
Q

What is the distribution of the 5ltr blood volume at rest?

A

Arteries and arterioles = 11%
Capillaries = 5%
Heart and lungs = 17%
Veins = 67%

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14
Q

What is Fick’s Law?

A

J = PA(Ci - Co)

Where: J = rate of transfer; P = permeability; A = area; and Ci - Co = Concentration gradient

How well did you know this?
1
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3
4
5
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15
Q

What is the hydrostatic pressure at the arteriolar end and the venular end?

A

~35mmHg and ~15mmHg

How well did you know this?
1
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2
3
4
5
Perfectly
16
Q

What is the coloid osmotic pressure?

A

25mmHg

17
Q

What is the net result of ‘Starling Forces’?

A

Filtration at the arteriolar end forming approx 20 litres of interstitial fluid; and reabsorption at the venular end (approx 17 litres back into plasma)

18
Q

Describe the metabolic needs of the brain

A

Constant - can be met by a flow of 0.5ml/min/g.

Extrememly intollerant to flow interuption.

Min = 750mls; Max = 750mls

19
Q

Describe the metabolic needs of the heart

A

At rest it needs 0.9ml/min/g. If it has to work hard, its requierment increases four fold.

Extremely intollerant to inadequate flow.

Min = 300ml; Max = 1200ml

20
Q

Describe the metabolic needs of the kidney

A

Requires constant high blood flow, though most flow is not nutritive. Flow can be moderated by need to defend composition of the fluid compartments of the body.

Min + Max = 1200ml

21
Q

Describe the metabolic needs of the gut (and liver)

A

Gut and liver are connected in series via the hepatic portal system. At rest recieves 1ml/min/g. Digestion of a meal generates substantial increase in flow.

Can tolerate short term flow reduction.

Min = 1400ml; Max = 2400ml

22
Q

Describe the metabolic needs of the skeletal muscles

A

Metabolic needs varies enormously. At rest flow needs to be 0.03ml/min/g, increasing to 6ml/min/g in exercise, but this may not meet metabolic needs.

Can survive a degree of anaerobic metabolism.

Min = 1000ml; Max = 16000ml

23
Q

Describe the metabolic needs of the skin

A

Not very metabolically active. May be supported by 0.03ml/min/g, which may increase to 0.1ml/min/g for thermoregulation.

Min = 150ml; Max = 500ml

24
Q

Describe the metabolic needs of the rest of the body

A

Fairly constant overall demand.

Min/max = 200ml

25
Q

What is the distribution of the 5ltr blood volume at rest?

A

Arteries and arterioles = 11%
Capillaries = 5%
Heart and lungs = 17%
Veins = 67%

Cardiovascular (5 decks)

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