intro

Question 1

drug

Answer 1

1) chemical substance that produces a biological effect for an intended purpose

Question 2

the ideal drug

Answer 2

1) effectiveness / efficacy
- ability to elicit response once bound to a drug target
2) safety / toxicity
- does the drug have toxic effects
- how much can we give
3) selectivity / affinity
- the binding strength of a drug to a target
- ability to discriminate between targets
- producing a single effect

Question 3

taurine

Answer 3

1) alleviates the symptoms of hypertension
2) beta 1 but not beta 3 containing receptors

Question 4

cytochrome p450

Answer 4

1) major drug metabolizing enzyme system
2) many drugs would be competing for this enzyme if you consume them at the same time
3) this system is expressed to varying degrees in different populations