Intro Flashcards

(42 cards)

1
Q

what is pharmacology

A

study of drugs that alter functions in living organisms

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2
Q

pharmacotherapy

A

use of drugs to prevent , diagnose, treat S & S

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3
Q

Where do drugs come from?

A

synthetic compounds in labs

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4
Q

what is classification based on?

A

effects on body systems, therapeutic uses, and chemical characteristics

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5
Q

What are prototypes?

A

individual drugs that represent groups of drugs

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6
Q

What does FDA do?

A

enforces the law; approves drugs for over the counter

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7
Q

When was the comprehensive drug abuse prevention and control act passed?

A

1970

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8
Q

What does the comprehensive drug abuse prevention and control act do?

A

regulates manufacturing and distribution of narcotics, depressants, stimulants, hallucinogens, and anabolic steroids

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9
Q

What is schedule 1?

A

most addictive and NOT accepted

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10
Q

What is schedule 5?

A

very low potential for abuse and addicition

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11
Q

What does the DEA enforce?

A

controlled substance act`

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12
Q

What is category A and X for pregnancy medications?

A

A= safest, X= known danger

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13
Q

What is Beers Criteria?

A

inappropriate for elderly

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14
Q

What does black box label mean?

A

strongest warning possible

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15
Q

what is a precaution on drug labels?

A

a consideration must be taken

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16
Q

What is a warning on drug labels?

A

serious adverse events have occurred

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17
Q

Where do drug actions occur?

A

cellular level

18
Q

What do drugs do to the body?

A

alter basic process in cells, inhibit normal cell function

19
Q

What is the purpose of transport pathways?

A

move drug molecules through the body and across cell membranes to reach adequate concentration

20
Q

Most meds are given for a ________ effect.

21
Q

What is the most common way of transport?

A

passive diffusion

22
Q

What is pharmacokinetics?

A

what the body does to the drug

23
Q

What are the 4 ways the body does pharmacokinetics?

A

absorption, distribution, metabolism, excretion

24
Q

What is absorption?

A

transmission of a drug from the administration route to the bloodstream

25
What is the rate of absorption?
how fast to take effect
26
What is the amount of med absorption?
intensity
27
What is the most common absorption route?
GI & injection
28
What are the routes?
oral, sublingual, buccal, rectal, vaginal, subc & IM
29
what is the barrier for oral/GI?
enteric and GI pH
30
what is the barrier for inhalation?
trouble inhaling and scarring in the lungs
31
what is the barrier for sub?
swallowing before dissolved
32
What is the barrier for rectal?
stool
33
What is bioavailability?
represents the amount of drug successfully reaching circulation
34
What is the key indicator of absorption?
bioavailability
35
What route is bioavailability lower due to first pass metabolism effect
All routes minus IV
36
What is the first pass metabolism effect?
medication reaching liver enzymes before intended site of action
37
How do we go around first pass?
enter the bloodstream directly or absorption through skin and lungs
38
What route doesn't undergo absorption?
IV
39
What has 100% bioavailability?
IV
40
What is distribution?
transportation of medication to sites of action via bodily fluids
41
What does distribution depend on?
adequacy of blood circulation
42
what impacts the process of distribution?
inhibited circulation and permeability of cell membranes