Intravascular Large B cell Lymphoma

Question 1

What is the definition of ILBL ?

Answer 1

• Intravascular large B cell lymphoma
  
  • selective growth of lymphoma cells with the lumina of vessels
  • exception is large arteries and veins

Question 2

What is the epidemiology and localization

of this tumor ?

Answer 2

• occurs in adults with a median age of 67 years of age
• M:F is 1.1:1
• lymphoma is usually widely disseminated
  
  • can involve any organ
  • lymph nodes usually are spared but bone marrow is usually involved

Question 3

What is the typical clinical presentation

of ILBL ?