Intracellular Compartments and Protein Sorting 2 Flashcards
Where are proteins synthesized?
on ribosome and imported into mitochondria
Most mitochondiral proteins are?
encoded in nuclear DNA
What mitochondiral membrandes does?
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What are the mitochondiral signal sequences?
N terminal and internal signal sequences
What do mitochondrial signal sequences form?
amphiphilic alpha helix
What do the ends of the mitochondrial seqence look like?
positively charges residues cluster on one end and uncharges hydrophobic on the other end of the helix
What does the specific receptor proteins recognize?
configuration rather than precise sequence
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Tom is
generic
Sam is specific
it allows insertion of proteins in outer membrane
TOM and TIM have 2 complexes what are they?
recetors for mitochondrial precurosr proteins
translocation channel
How do protiens get into mitochondrial matrix?
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