Intestine Flashcards
Meckel’s Diverticulum
Incomplete involution of vitelline duct; congenital outpouching disorder
Rule of 2 (*KNOW FOR EXAM) – 2% of normal population, within 2 feet of ileocecal valve, average 2 inches in length
commonly asymptomatic
Malabsorption Syndromes in Small Intestine
secretion insufficiency, impaired motility with bacterial overgrowth and bile salt inactivation, impaired mucosal function
Defective absorption of fats, fat soluble and other vitamins, proteins, carbohydrates, electrolytes, minerals and water
Clinically present with chronic diarrhea
Typically fatty feces (steatorrhea)
Celiac disease (
enteropathy triggered by ingestion of gluten containing diet
proximal part of intestine
here is HLA association with celiac disease
Marked atrophy and loss of villi
serologic tests for GSE
tTg use dcurrently, AGA used in past
Intestinal obstruction
More common in small bowel
Numerous causes – luminal (within lumen), intramural (within bowel wall), extramural/mechanical causes
Pseudo-obstruction – no localized lesion,
Intramural
Congenital atresias (fistula)
Inflammatory conditions – Crohn’s TB, drug-induced stenosis, ischemic strictures, radiation damage, polypoid or infiltrative neoplasms
Extramural
all require surgical intervention)
Generally diseases of peritoneum – congenital mesenteric/omental bands, peritoneal tumors
Intussusception – telescoping of proximal bowel segment into distal (in adults, often due to tumor)
Volvulus – twisting of bowel loop