Intervertebral disc Flashcards
What isthe number of true intervertebral discs identified in the adult
Twenty-three
In the adult, which vertebral levels will demonstrate a true intervertebral disc
Those between C2 and S1 inclusive
What is the length of the intervertebral disc contribution to the vertebral column length
about seven inches
What is the pervent of intervertebral disc height contribution to the length of each region of the vertebral column
Cervical 22-25%
Thoracic 20%
lumbar 33%
What are the names of the central peripheral and horizontal zones of the intervertebral disc
Nucleus pulposus = central zone
annulus fibrosus = peripheral zone
cartilaginous end plate = horizontal zone
What is the water concentration in the lumbar nucleus pulposus at birth and after thirty
Birth 88%
thirty 70%
What is the consequence of non-aggregated glycosaminoglycans in the lumbar nucleus
the nucleus pulposus will lose water under deformation conditions
What cell is associated with the nucleus pulposus until about age eleven
Notocohord cells
Which type of collagen is dominant in the nucleus pulposus
Collagen type II
What is the organizational pattern for collagen fibers in the nucleus pulposus
They are irregularly orientated and randomly scattered
What is the appearance of the cervical annulus fibrosus
A horse-shoe with the anterior margin thick and the lateral margins tapering to the uncinate processes; the posterior margin is thin
What compensates for the thiness of the posterior part of the cervical annulus fibrosus
Posterior longitudinal ligament
What is the organization of the lumbat annulus fibrosus
it has 12-14 concentric cylindrical lamellae
What is the water concentration in the lumbar annulus fibrous at birth and after thirty
Birth 78%
Thirty 70%
What is the organizational pattern for glycosaminoglycans in the lumbar annulus fibrosus
They typically have a binding site for hyaluronic acid and are thus aggregated
Which type of collagen is dominant in the annulus fibrosus
Collagen type 1
What is the organizational pattern for collagen fibers in the annulus fibrosus
They are parallel with one another in a single lamellus and angled
What is the attachment site for collagen fibers within the annulus fibrosus
Collagen fibers of the outer lamellae will become Sharpey’s fibers and penetrate the epiphyseal rim
Collagen fibers of the inner lamellae will attach to the cartilaginous end plate
What is the origin for the cells of the annulus fibrosus
Sclerotomites
what part of the vertebral body upper and lower surfaces will the cartilage end plate not cover
The epiphyseal rim
What is the principal type of collagen fiber within the cartilage end plate
The type II collagen fiber
what is the direction of collagen fibers within the cartilage end plate
Collagen fibers are aligned anterior to posterior
What is the attachment site for collagen fibers of the inner lamellae of the annulus fibrosus
the cartilaginous end plate
What are the types of receptor endings in the intervertebral disc
Nociceptors and proprioceptros
