interstitial lung disesase Flashcards
what are the principle features of ILD?
dyspnoea
dry cough
restrictive spirometry
abnormal CXR/CT
what are the groups of causes of iLD?
environmental
drugs
hypersensitivity
infection
idiopathic (IPF)
what are the environmental causes of ILD?
asbestosis
silicosis
what are the drug causes of ILD?
BANS ME
bieomycin, busulfan
amiodarone
nitrofurantoin
sulfasalazine
methotrexate, methysergide
what are the hypersensitivity causes of ILD?
extrinsic allergic alveolitis EAA
what are the infectious causes of ILD?
TV
viral
fiungi
what systemic diseases is ILD associated with?
sarcoidosis
rheumatoid arthritis
SLE, systemic sclerosis, sjogrens, mixed connective tissue disease MCTD
ulcerative colitis
ankylosing spondylitis
what are the causes of ILD if it affects upper zone?
A PENT
aspergioliosis- ABPA
pneumoconiosis- coal, silica
extrensic allergic alveolitis
negative sero-arthoropathy
TB
what are the causes of ILD if it affects lower zones?
STAIR
sarcoidosis- mid zone
toxins- (drugs BANS ME)
asbestosis
Idiopathic pulmonary fibrosis
rheum- RA, sle, scleroderma, Sjogrens, PM/DM
what is silicosis?
Silicosis is a fibrosing lung disease caused by the inhalation of fine particles of crystalline silicon dioxide (silica). It is a risk factor for developing tuberculosis (silica is toxic to macrophages).
an example of a pneumoconiosis, a class of lung disease characterised by inhalation of (usually occupational) dust.
what are occupations at risk of silicosis?
mining
slate works
foundries
potteries
what are scan features of silicosis?
upper zone fibrosing lung disease
‘egg-shell’ calcification of the hilar lymph nodes
