Interpreting Lab Tests Flashcards

1
Q

What are some reasons for elevated Hb?

A

dehydration
severe lung disease
heavy smoking

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2
Q

what are some reasons for Hb to fall below normal?

A
  • iron, B12, or folate deficiency
  • cirrhosis
  • kidney disease
  • bleeding
  • cancers that affect the bone marrow
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3
Q

what are some causes for elevated WBC count?

A
bacterial infections
trauma
intense exercise
stress
heavy smoking
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4
Q

what are some causes for decreased WBC count?

A
  • chemotherapy
  • radiation therapy
  • diseases of the immune system
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5
Q

what are neutrophils for?

A

fight bacterial infection

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6
Q

what are lymphocytes for?

A

T-cells: attack and kill germs/ regulate immune system

B-cells: make ab

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7
Q

what are monocytes or macrophages for?

A

fight infections

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8
Q

what are eosinophils for?

A

involved in allergies and reactions to parasites

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9
Q

what are basophils for?

A

long term allergic response? not well understood.

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10
Q

what drugs may increase WBC count?

A

aspirin

heparin

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11
Q

what are drugs that may decrease WBC count?

A

chemotherapy drugs

diuretics

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12
Q

BMP includes what values?

A
  1. electrolytes: Na+, K+, Cl-, CO2
  2. glucose
  3. Ca2+
  4. BUN
  5. creatinine
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13
Q

what causes hypernatremia (increased Na+)?

A

dehydration, renal failure, cardiac failure

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14
Q

what can cause hyponatremia?

A

vomiting, diarrhea

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15
Q

if BUN is elevated but creatinine is normal, what is the most common reason for this occurence?

A

dehydration

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16
Q

what is the difference btwn BMP and a CMP?

A

CMP is basically a BMP plus a liver profile (liver enzymes and albumin)

17
Q

what is albumin a marker for?

A

overall general nutrition which is important for healing

18
Q

what level of albumin and lymphocytes can be used as a predictor of healing in diabetic patients?

A

albumin difficulty healing

albumin >3 & lymphocytes > 1500/mm3 –> healing chances increase

19
Q

which test is administered when administering heparin?

A

PTT (partial thromboplastin time)

20
Q

which test(s) is administered with warfarin administration?

A

PT and INR

21
Q

what does a prolonged or increased PT/PTT mean?

A

blood is taking too long to form a clot

22
Q

which pathway does PT affect?

A

extrinsic pathway

23
Q

which pathway does PTT affect?

A

intrinsic pathway

24
Q

what is the therapeutic level of INR to decrease risk of clot formation?

25
when is ESR used?
measures inflammation; used as a baseline for a patient with a suspected infection
26
what is the timescale for an ESR?
increase occurs slowly over 10-14 days and decreases slowly
27
what is the cutoff point for an ESR that is strongly suggestive of osteomyelitis?
>70
28
what tests should you order if you suspect an infectious process?
ESR and CRP
29
what is the timescale for CRP?
unlike ESR, it increases rapidly over several days and returns to baseline in a week
30
what is the cutoff point for CRP to indicate osteomyelitis?
CRP > 3.2 with an ulcer >3mm in depth suggests osteomyelitis
31
uric acid is not a great tool for acute gout- why?
uric acid levels increase typically before patient exhibits clinical symptoms
32
what are the 3 isoenzyme forms of CK?
CK-MB: cardiac muscle CK-MM: skeletal muscle CK-BB: brain
33
aldolase is increased in skeletal muscle disease.
true
34
what does gout crystals look like?
- monosodium urate - negatively birefringent - long, thin, pointed
35
what does pseudogout crystals look like?
- calcium pyrophosphate - positively birefringent - shorter, less sharp