Internal organs Flashcards

1
Q

Ureter

A

Retroperitoneal
Renal artery
Tunica adventitia-blood vessels, loose CT, adipose tissue, nerves

Conducts urine from renal pelvis to urinary bladder
24-34cm

Lamina mucosa- transitional epithelium

Lamina propria- dense CT
Tunica muscularis - inner longitudinal, middle circular, outer longitudinal

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2
Q

Urinary bladder

A

Located in pelvis behind pubic symphysis

Tunica mucosa- lamina epithelium - transitional
Lamina propria- - loose CT

Sympathetic nerve supply - hypogastric plexus
Parasympathetic - pelvic splanchic nerve

Internal urethral sphinctor has 3 openings - 2 for ureter and 1 for urethra

Hollow muscular organ
Smooth muscle of bladder wall
Detrusor muscle - contraction compresses the entire organ and forces urine into urethra

Tunica serosa - loose CT covers superior surface of bladder

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3
Q

Urethra in males

A

Fibromuscular tube
Serves as the terminal duct for both the urinary and genital systems
20cm long

Prostatic urethra -extends from the neck of the bladder through the prostate gland. Lined with transitional epithelium.

Membraneous urethra - extends from the apex of the prostate gland to the bulb of the penis

Penile urethra - extends from about 15cm through the length of the penis and opens on the body surface at the glans penis

Lined with pseudostratified epithelium
Lined with stratified squamous epithelium at its distal end
Ducts of Cowper’s glands and glands of Lifted empty into penile urethra

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4
Q

Urethra in females

A

3-5cm long
It’s mucosa has longitudinal folds
Lined with transitional epithelium, but stratified squamous before its termination
Urethral glands open into the urethral lumen

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5
Q

Testis

A

Suspended by spermatic cords
Connected to the scrotum by scrotal ligaments

When descending from the abdominal cavity, into the scrotum they carry with them:
Blood vessels
Lymphatic vessels
Autonomic nerves
Tunica vaginalis - extension of the abdominal peritoneum.

Tunica albuginea:
A CT capsule that covers each testis

Tunica vasculosa:
Inner part of tunica albuginea
Loose CT layer and contains blood vessels

Each testis is divided into 250 lobules by incomplete CT septa.

Each lobule consists of 1-4 seminiferous tubules in which sperm are produced.
Has CT stroma in which leydig cells are.
Consists of seminiferous epithelium surrounded by a tunica propria.

Complex stratified epithelium, containing 2 cells: sertoli cells and spermatogenic cells.

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6
Q

Epididymis

A

Crescent shaped
Lies along superior and inferior surfaces of the testis
Consists of efferent ductules and the duct of the epididymis and associated vessels, smooth muscle and CT coverings

Divided into:
Head - efferent ductules
Body
Tail - both duct of epididymis

Duct of epididymis is lined with pseudostratified columnar epithelium.
Contains: principle cells and basal cells.

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7
Q

Seminal duct

A
A tube serving as an efferent duct of the testis
Made up of the tubules of the: 
Epididymis
Vas deferens
Ejaculatory duct

Vas deferens:
A direct continuation of the tail of the epididymis

Enters the abdomen and passes through the inguinal canal as a component of the spermatic cord
After leaving the spermatic cord, it descends in the pelvis to the level of thebladder, where its distal end enlarges to form the ampulla

Lined with pseudostratified columnar epithelium
Columnar cells with microvilli
Rounded basal cells rest on basal lamina.

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8
Q

Spermatic cord

A

Formed by the vas deferens and surrounding tissue that run from the inguinal ring down to each testicle

Ensheathed in 3 layers:
External spermatic fascia
Cremasteric muscle and fascia
Internal spermatic fascia

Contains:
Testicular artery
Deferential artery
Cremasteric artery

Nerves:
Genital branch of the genitofemoral nerve
Sympathetic nerves
Ilio-inguinal nerve

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9
Q

Seminal vesicle

A

Paired, highly folded tubular glands
Located on posterior wall of bladder.

It’s wall contains:
A mucosa
A layer of smooth muscle
A fibrous coat

Pseudostratified columnar epithelium has columnar cells - secretions are whitish yellow

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10
Q

Prostate

A

Largest accessory sex gland of males
Located in pelvis, inferior to bladder

Consists of 30-50 tubuloalveolar glands arranged in 3 concentric layers:
Inner mucosal layer
Intermediate submucosal layer
Peripheral layer

Peripheral layer contains main prostatic glands
Glands of the mucosal layer secrete into the urethra

Zones of the adult prostatic parenchyma:
Peripheral zone
Central zone
Transitional zone

Periurethral zone - contains mucosal and submucosal glands

Parenchymal epithelium is simple columnar
Smooth muscle in the stroma.

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11
Q

Bulbo-urethral gland

A

Paired, pea-sized structures
Located in urogenital diaphragm

The duct of each gland passes through the inferior fascia of the urogenital diaphragm and joins the initial portion of the penile urethra

Composed of the tubulo-alveolar glands

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12
Q

Penis

A

Has a root: made upnof the bulb and the right and left crura
Has a body: consists of the 3 cylinders of erectile tissue enclosed in a tubular sheath of fascia:
2 dorsal masses (corpus cavernosa)
A ventral mass (corpus spongiosum) - spongy part of urethra is embedded

Tunica albuginea:
Dense, fibroelastic layer
Bindsnthe 3 cylinders together and forms a capsule around each one

Corpora cavernose:
Contains vascular spaces
Lined with vascular endothelium
Surrounded by a layer of smooth muscle that forms trabeculae within tunica albuginea
Derived from helicine arteries 

It’s skin:
Thin loosely attached to underlying CT, very think and tightly attached to the glans

The prepuce - fold of skin that covers glans

Sebaceous glands - in the skin of the penis, just proximal to the glans

Transitional epithelium - lines prostatic part of urethra
Pseudostratified to stratified columnar epithelium - lines the membranous and spongy portions

Stratified squamous in spongy urethra - has goblet and intraepithelial glands.

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13
Q

Scrotum

A

A dual chambered proturbance of skin and muscle - contains testicles.
Divided by septum

Anterior scrotal artery and posterior scrotal artery. Testicular vein.

Innervation:
Posterior scrotal nerves
Anterior scrotal nerves
Genital branch of genitofemoral nerve
Perineal branches of posterior femoral cutaneous nerve. 

Superficial inguinal lymph nodes - keep temp of body slightly lower than the rest of the body

Superficial fascia - has smooth muscle
Spermatic fascia - derived from 3 layers of anterior abdominal wall: external spermatic fascia
Cremasteric fascia
Internal spermatic fascia

Tunica vaginalis - lies within the 3 spermatic fascia, a closed sac

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14
Q

Uterine tube

A

Paired tubes
Transport the ovum from the ovary to the uterus
Provide the environment for the fertilisation and initial development of zygote to the morula stage

Segments:
The infundibulum - funnel shaped segment

The ampulla - longest segment of the tube, site of fertilisation

The isthmus - narrow segment

The uterine part - lies within uterine wall
Opens into the cavity of the uterus

Mucosa: inner lining of uterine tube
Has longitudinal folds which project into lumen of uterine tube

Muscular is has: inner circular layer
Outer longitudinal layer

Serosa: the outermost layer of uterine tube
Has endothelium and layer of CT

Mucosal lining is simple columnar epithelium which has ciliated cells and non ciliated cells

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15
Q

Uterus

A

Receives the developing morula from the uterine tube - embryonic and fetal development occur here

Located between bladder and rectum

Has 2 regions: body - large upper portion, anterior surface is flat, posterior surface is convex

Cervix- lower, barrel shaped part, separated from the body by the ishmus

Uterine wall has 3 layers, outward to in:
Endomettium - mucosa of the uterus
Myometrium - thick muscular layer
Perimetrium - outer serosal layer, has mesothelium, has a layer of loose CT, covers posterior part of uterus and part of anterior surface.
Remaining part of anterior surface consists of CT or adventitia

During reproductive life, endomettium consists of 2 layers: functional layer which proliferates and degenerates during menstrual cycle. The basal layer is retained during menstruation.

Endomettium: lined by simple columnar epithelium and has ciliated and secretory cells.

Surface epithelium invaginates into underlying lamina propria, forming uterine glands - simple tubular glands.

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16
Q

Vagina

A

A fibromusculae sheath extending from the cervix to the vestibule.
Vaginal wall consists of:
Inner mucosal layer - has transverse folds
Stratified squamous non-keratinised epithelium
It’s surface is lubricated by mucous produced by cervical glands

Intermediate muscular layer:
Has 2 smooth muscle layers - outer longitudinal layer and inner circular layer.

Outer adventitial layer - has an imner ndense CT layer and an outer loose CT layer

17
Q

External genitalia

A

Stratified squamous epithelium

Mons pubis:
Rounded prominence over the pubic symphysis
Formed by subcutaneous adipose tissue

Labia mojor:
2 large longitudinal folds of skin
Extend from the !one pubis
Contain a layer of smooth !muscle and subcutaneous adipose tissue
Outer surface is covered with pubic hair
Inner surface is smooth and no hair
Sebaceous and sweat glands are present on both surfaces

Labia minor
Paired, hairless folds of skin that border the vestibule
Has a core of CT within each fold
Contains blood vessels and has sebaceous glands in the stroma

Clitoris:
Erectile structure - has 2 small erectile bodies, the corpora cavenosa
A small rounded tubercle of erectile tissue
Skin over the glans is thin and contains sensory nerve endings

Vestibule:
Lined with stratified squamous!oua epithelium
Has mucous, skene’s and bartholin’s glands

18
Q

Mammary gland

A

Modified apocrine sweat gland
When inactive it is composed of 15-20 irregular lobes of branches tubuloalveolar glands - separated by fibrous bands of CT
Has a papilla(nipple)

Areola contains:
Sebaceous glands, sweat glands and modified mammary glands
End in lactiferous duct

Lactiferous sinus:
Dilated portion of the duct
Stratified squamous epithelium at opening
Double layer cuboidal cells at the lactiferous sinus
Single cuboidal or columns cells in secretory portion of the gland

Secretory cells produce:
Merocrine secretion
Apocrine secretion

Colostrum - secretion released after childbirth

19
Q

Pituitary gland

A

Pea sized structure found in the sella turcica
Infundibulum - connects the hypothalamus to the pituitary gland

2 lobes
Anterior lobe:
Derived dro! Ectoderm of oropharynx
Glandular epithelial tissue
Consists of 3 deriviates- pars tuberalis, pars intermediate, pars distalis

Posterior lobe:
Pars nervosa - has supraoptic and paraventricular nuclei
Infundibulum

Anterior lobe hormones:
ACTH, TSH, FSH, LH, GH, PROLACTIN

Parenchymal cells in anterior pituitary - somatotropes:
Produce GH and regulated by GHRH

Lactotropes: produce PROLACTIN - inhibited by dopamine and stimulated by TRH

Corticotropes: prodcue ACTH - regulated by CTRH

Gonadotropes: produce LH and FSH - regulated by GnRH

Thyrotropes: produce TSH - regulated by TRH

20
Q

Pineal gland (epiphysis)

A

Endocrine gland
Regulates daily body rhythm
Attached to the brain by a short stalk
Located on posterior wall of 3rd ventricle

Parenchymal cells of the pineal gland
Pinealocytes: arranged in clumps or chrods within lobules

Interstitial cells: corpora arenacea - calcified concretions
Good marker for radiographic studies
Regulates circadian rhythm
Obtains information about light and dark cycles from the retina via the retinohypothalmic tract

Melatonin: released in the dark
Regulates reproductive function by inhibiting steroidogenic activity of the gonads - influences sexual activity

Neurotransmitters of the pineal gland:
Serotonin, dopamine, norepinephrine

21
Q

Thyroid gland

A

Consists of 2 lateral lobes connected by an isthmus - thin band of thyroid tissue

Secretory follicles - its wall has simple cuboidal or low columnar epithelium (follicular cells)

Cells in then follicular epithelium:
Follicular cells - produce T3 and T4

Parafollicular cells - in periphery of follicular epithelium and secrete calcitonin.
It’s function is important to normal growth and development.

Hormones produced: thyroxine T4
Triiodothyronine T3
Calcitonin

22
Q

Parathyroid glands

A

Endocrine glands
Located in connective tissue on posterior surface of lateral lobes of thyroid gland

Arranged in 2 pairs: superior parathyroid gland and inferior parathyroid gland

Surrounded by a connective tissue caosule that separates it from the thyroid

Septa - extends from the capsule into the gland to divide it into lobules

Epithelial cells of parathyroid gland:
Principal cells - secrete PTH
Oxyphil cells