Internal Medicine Flashcards
ECG Leads: V1 - V6
Anterior
LAD
ECG Leads: II, III, avF
Inferior
RCA, LCX
ECG Leads: V1 - V3
Posterior
RCA – I, avL (depression)
LCX – I, avL (elevation)
ECG Leads: I, avL, V5, V6
Lateral
LCX, diagonal
ECG Leads: V4-V6R
Right Ventricle
RCA
anasarca + pulmonary/facial edema + hypertension + abnormal u/a with proteinuria and microscopic hematuria =
acute nephritic syndrome
CAP + arthralgias + erythema nodosum/multiforme =
Coccidiodies (Valley Fever)
Development of _____ _____ in a patient with infective endocarditis should raise suspicion for _____ _____ extending into the adjacent cardiac conduction tissues.
AV block
perivalvular abscess
Factors that differentiate tricuspid vs. aortic endocarditis (2)
- TV endocarditis usually presents with a holosystolic murmur (AR)
- Cardiac conduction abnormalities are mrore common with aortic valve involvement
Dobutamine (beta 1 agonist) works by…
improving ejection fraction AND reducing left ventricular end-systolic volume
Liver Failure: Portal HTN Sx
Esophageal varices Splenomegaly Ascites Caput medusae Anorectal varices
Liver Failure: Hyperestrinism Sx
Spider angiomas Gynecomastia Loss of sexual hair Testicular atrophy Palmar erythema
Pathohysiology of AML
atypical promyelocytes in the bone marrow
Malaria prophylaxis for India
Chloroquine resistance; prophylaxis with mefloquine; begins 2 weeks before travel and continued 4 weeks after returning
Sick Sinus Syndrome (SSS) Definition
inability of SA node to generate an adequate heart rate
SSS EKG Findings
3-6 seconds with no sinus nodal activity + dizziness
DX: low cortisol + high ACTH + hyper pigmentation + hyponatremia + hyperkalemia =
Primary Adrenal Insufficiency; likely due to autoimmune etiology
G6PD Deficiency
X-linked; Black men; Episodic hemolysis in response to Rx, illness, etc.; Heinz bodies and bite cells seen on peripheral smear
Management of severe hypercalcemia
Aggressive fluids
Calcitonin
+/- Pamidronate (takes 2-4 days to work)
Round face + bruises think…
Cushing’s
HTN + hyperglycemia + weight gain =
Cushing’s
DOE + HTN + prominent pulmonary arteries + enlarged R heart border =
Pulmonary HTN
Arsenic Poisoning
Polyneuropathy
Pancytopenia
Mild LFT elevation
Skin Lesions
Type of HTN Rx that has been proven to slow the progression of end-organ damage in patients with DM2…
ACE inhibitors
Bilateral hilar adenopathy on CXR
Sarcoidosis
Pathophysiology of sarcoidosis
chronic granulomatous inflammation; noncaseating granulomas
Hypopituitarism Features (3)
Glucocorticoid deficiency
Hypogonadism
Hypothyroidism
Splenic infarction usually occurs due to…
hypercoagulable states
embolic disease
hemoglobinopathy
Usually (this condition) is asx; however, it can be exacerbated by air travel and/or dehydration
sickle cell trait
Elderly patient + severe lymphocytosis + hepatosplenomegaly + lymphadenopathy + bicytopenia (anemia, thrombocytopenia)
CLL
Diagnostic tool for CLL
Flow cytometry of the peripheral blood
Claw toes in an elderly patient are most likely due to…
diabetic neuropathy
Management for acute limb ischemia s/p MI
immediate anticoagulation, vascular surgery consultation, transthoracic echo
Addison’s Disease (AKA primary adrenal insufficiency) presents with this acid-base disturbance:
normal anion gap acidosis
Elevated anion gap metabolic acidosis causes:
DKA
Intoxication
Tissue Hypoxia
Renal Failure
Metabolic alkalosis causes:
Vomiting
Hyperaldosteronism
Excessive Volume Contraction
Respiratory acidosis causes:
Conditions that impair proper ventilation = hypoventilation
Respiratory alkalosis causes:
Conditions that impair proper ventilation = hyperventilation
Leukoplakia
Presents as white patches or plaques over the oral mucosa that usually can NOT be scraped off; R/F include smokeless tobacco and alcohol use
Primary lymphoma of the thyroid is characterized by…
rapidly progressive thyroid enlargement with compression of surrounding structures; more common in patients with a PMH of Hashimoto thyroiditis
Test to rule in RA =
anti-CCP antibody
When a patient presents with carpal tunnel, you must also r/o this condition
RA (order inflammatory factors, RF, and xrays)
LFTS >3000 think…
Ischemic hepatic injury
Tx for hyperkalemia w/ EKG changes
calcium gluconate
Most common cause of asx elevated alk phos in elderly patient is:
Paget disease of the bone
XR findings for Paget’s disease of the bone:
osteolytic/mixed lytic-sclerotic lesions
All pts with RA should be on…
DMARDS, specifically methotrexate
Dyspepsia + postprandial fullness + nausea in the context of a patient that is from a low income country
Helicobacter pylori
Pathophysiology of H. pylori
urease-producing bacterial infection
Three most common causes of aortic stenosis:
- senile calcific aortic stenosis (>70)
- bicuspid aortic valve
- rheumatic heart disease
Patients with ankylosing spondylitis can develop ______ due to diminished chest wall and spinal mobility.
restrictive lung disease
PFTs for patient with ankylosing spondylitis show…
mildly restrictive pattern with reduced VC and TLC
Wart like “rash” in groin region that is NOT flesh colored…
HIV - Kaposi’s Sarcoma
Acid in eye =
WATER FLUSH
Prevalence is high, _____ is high.
PPV
Prevalence is low, _____ is high.
NPV
Left sided diastolic heart failure due to…
MI
4th heart sound due to…
MI
DX: substernal discomfort + left-sided neck pain + diaphoresis + dyspnea
acute MI
Loss of p waves =
A.Fib
Anion gap =
Na - (Cl + BiCarb)
Winter’s Formula =
1.5 * (BiCarb) + 8 (+/- 2)
Normal pH
7.35 - 7.45
Normal BiCarb
22-28
Normal CO2
33-45
Electrolyte imbalance that is the best predictor for severity of heart failure =
hyponatremia
IBD that is bloody =
UC
IBD that is non-bloody =
Crohn’s
Warfarin + acetiminophen =
BLOOD
Warfarin + green foods =
CLOT
Number Needed to Treat Formula =
Inverse of Absolute Risk Reduction
Tx for minor frostbite
Rapid rewarming with warm water
Acute goat path findings:
needle shaped spindles
HIV patient with multiple non-enhacning brain lesions
PML
Tx for pulmonary HTN
ACE + diuretic
Cor pulmonale is usually caused by…
impaired function of the R ventricle secondary to pulmonary htn
Ejection click + crescendo-decrescendo systolic murmur over L second intercostal speace
Pulmonic valve stenosis
OSA can cause transient periods of hypoxemia which leads to…
polycthemia; the kidney responds by increasing erythropoietin
Drug for recurrent nephrolithiasis secondary to hypercalcemia
Thiazide diuretics
Febrile nonhemolytic transfusion reaction
occurs within 1-6 hours; fever, chills, nausea, and malaise; prevent by leukoreduction
Most common cardiac S/E with SLE
acute pericarditis
Bullae on erythematous background
bullous pemphigoid
Bullous pemphigoid tx
topical clobetasol
Hyperthyroidism + increased RAIU =
de novo thyroid hormone synthesis
Hyperthyroidism + decreased RAIU =
preformed hormone, exogenous hormone intake
Shoulder pain + horner =
pancoast tumor
Choice of drug for patients that are allergic to penicillin but have primary syphillis
Doxycycline
Lithium can cause…
nephrogenic diabetes insipidus
Tx for lithium DI =
d/c lithium, salt restriction
Most common type of cancer associated with asbestos
bronchogenic carcinoma
Pleural plaques
Asbestos
Test for Sjogren Syndrome
Antibodies to Ro/SSA and La/SSB
Sx of Sjogrens
dry mouth difficulty swallowing thrush dental caries dry eyes
Sx of SLE
photosensitive rash
symmetric oligoarthritis
SLE + hx of PE/DVT + hx of miscarriages
antiphospholipid syndrome
Dx finding in patients with antiphospholipid syndrome
prolonged PTT
Unilateral uptake on RAUI scan…
toxic adenoma = autonomous thyroid production
Lynch Syndrome
Colon
Endometrial
Ovarian
What part of the spine does RA affect first?
Cervical
Obesity hypoventilation syndrome
high BMI
daytime hypercapnia
alveolar hypoventilation
Erysipelas
superficial skin rash that has raised, sharply demarcated borders; caused by Group A Strep
Cardiac index = reduced; PCWP = increased
Cardiogenic shock secondary to MI
Cold water immersion works by…
slowing AV node conduction
Massive PE would cause this heart problem…
RV dysfunction
Metabolic acidosis to alkalosis in a patient with ascites…
+ loop diuretic
Slowly growing papule with irregular borders
BCC
Familial hypocalciuric hypercalcemia
mutation in the calcium-sending receptor; benign d/o characterized by elevated calcium, normal/elevated parathyroid hormone, low calcium excretion
Most common cause of back pain
lumbosacral strain
Felty Syndrome
inflammatory arthritis
splenomegaly
neutropenia
Achalasia
chronic dysphagia with both solids and liquids; better when standing up; classic bird beak finding on barium swallow
Tx of uric acid stones
high fluids
potassium citrate
Dx test for fibromuscular dysplasia
CT angio of abdomen