Interleukins Flashcards

1
Q

IL-1

A
  • Produced by = macrophages, B cells
  • Target cell = macrophages, B cells, T cells
  • Function = lymphocyte activation, macrophage stimulation
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2
Q

IL-2

A
  • Produced by = T cells
  • Target cell = T cells
  • Function = T cell proliferation/differentiation
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3
Q

IL-4

A
  • Produced by = T cells
  • Target cell = B cells, T cells
  • Function = B cell growth factor, isotype selection
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4
Q

IL-6

A
  • Produced by = B cells, T cells
  • Target cell = B cells
  • Function = B cell differentiation
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4
Q

IL-10

A
  • Produced by = T cells
  • Target cell = Th1 cells
  • Function = Inhibits cytokine synthesis
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5
Q

IL-12

A
  • Produced by = Monocytes
  • Target cell = T cells
  • Function = Induce Th1 cells
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6
Q

IL-17

A
  • Produced by = T cells
  • Target cell = Macrophages
  • Function = Induce inflammatory responses
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7
Q

1L-23

A
  • Produced by = Macrophages
  • Target cell = Memory T cells
  • Function = Promotes Th17 response
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