Interleukins Flashcards
1
Q
IL-1
A
Stimulates IL-6 and increases vascular endothelium permeability
2
Q
IL-6
A
Liver: Production of acute phase proteins and fever (inflammation)
3
Q
IL-8
A
Activation of neutrophils and activation of vascular endothelium
4
Q
IL-12
A
NK cells—activates them and promotes lymphocyte differentiation
5
Q
TNF-⍺
A
Increased permeability and activation of vascular endothelium
6
Q
IL-12
A
Influences Th0 cells to differentiate into Th1 cells
7
Q
IL-4 & IL-10
A
Influences Th0 cells to differentiate to Th2 cells which stimulate B cells to differentiate into plasma and memory cells
8
Q
IL-6, IL-21, TGF-β
A
Promote generation of Th17 which promotes the recruitment of neutrophils and inflammation and anti-microbial immune responses.
