Intercellular Signaling (homework questions) Flashcards

1
Q

Secreted by glands into capillary and has target organs reached by blood

A

Endocrine

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2
Q

Secreted by neurons into capillary and has target organ reached by blood

A

Neuroendocrine

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3
Q

Released by axon terminals of neurons into the synaptic junction, acts locally

A

Neurotransmitters

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4
Q

Secreted by cells into extracellular fluid and effects neighboring cells of a different type

A

Paracrine

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5
Q

Secreted by cells into extracellular fluid affects the function of the same cells that produced them

A

Autocrine

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6
Q

Which biochemical class of endocrine molecules is stored in secretory vesicles?

A

Proteins and polypeptides

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7
Q

Which biochemical class of endocrine molecules needs a transport plasma protein to travel in the blood?

A

Steroid

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8
Q

Which biochemical class of endocrine molecules binds to a nuclear or cytoplasmic receptor for its function?

A

Steroid

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9
Q

What is the name of the class of endocrine molecules derived from the amino acid tyrosine?

A

Catacholamines

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10
Q

Which hormone, derived from an AA, acts like a steroid?

A

Thyroid hormone

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11
Q

Name the three polypeptide growth factors

A
  • Mitogens
  • Trophic factors
  • Chemoattractants
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12
Q

What do mitogens do?

A

Stimulate cell proliferation (mitosis)

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13
Q

What do trophic factors do?

A

Growth & survival

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14
Q

What do chemoattractants do?

A

Gradient for mobile (WBC) cells (inflammation)

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15
Q

What cells produce histamine?

A

Mast cells

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16
Q

Where are mast cells located?

A

CT of bronchi and intenstines

17
Q

What is the function of the H1 histamine receptors in venules?

A

Causes venules to vasodilate, increasing tissue swelling and WBC infiltration into the tissue

18
Q

Name the location of the H2 histamine receptor

A

Stomach

19
Q

What is the mechanism of action for the release of stomach acid?

A

Histamine binds to H2 receptors in the stomach

20
Q

What AA is necessary to form nitric oxide?

A

Arginine

21
Q

What enzyme does nitric oxide turn on?

A

Nitric oxide synthase