Interactions Flashcards

1
Q

Nature of interaction between statin and Macrolides

A

Increase exposure of statin
monitor rhabdomyolsis
Dose adjustment

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2
Q

Tramadol + seizure

A

Reduced seizure thresholds

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3
Q

Lithium + sumatriptan

A

Serotonin syndrome

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4
Q

Amiodarone + Amitriptyline

A

Neurotoxicity

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5
Q

Fluconazole and SSRI (Citalopram & escitalopram)

A

QT prolongation

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6
Q

Omeprazole + clopidogrel

A

Decrease efficacy of clopidogrel

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7
Q

Quinolone + NSAID

A

Seizure

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8
Q

Tramadol + Sertraline

A

Serotonin syndrome

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9
Q

Doxycycline + warfarin

A

Increase INR

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