Inter and Intra Molecular Interactions Flashcards
Biochemistry relies on covalent or noncovalent molecular interactions?
noncovalent
Is covalent or non-covalent stronger?
Covalent
T/F: noncovalent molecules are bigger and not additive
F, they’re smaller and additive
Examples of noncovalent interactions:
- charge charge interactions
- van der waals forces
- dipole dipole interactions
- london dispersion forces
Charge charge interactions follow which law?
Coulomb’s law
F=k(q1q2/er2)
Common ions in the human body are…
- Ca2+
- Na+
- K+
- Mg2+
- Cl-
- HOPO42-
Energy of interaction is the amount of E needed…
to separate the two charged particles
Higher the dielectric constant =
weaker the interaction between charges
T/F: a salt bridge is the simplest charge-charge interaction
T
Dehydration alters
H bonding network b/c less water
Net result of dehydration is…
increased strength in charge-charge interactions at same distance
Major way ethanol effects charge-charge interactions:
contributes to dehydration
Minor way ethanol effects charge-charge interactions:
- high amounts of ethanol would alter the medium, which will strengthen electrostatic interactions
Dehydration would lead to a higher/lower dielectric constant
lower
Lower dielectric constant alters ion reactions b/c…
oppositely charged ions would have greater attraction and be less available for reactions
H bonds are the interactions between…
a covalently bonded H on a donor group and a pair of bonded e- on acceptor group
H bonds are partially…
dipole-dipole interaction and covalent
H bonds are important in biochem b/c…
of the quantity (a lot)
H bonding stabilizes…
structural elements
Permanent dipole dipole interactions results from…
differences in electronegativity between atoms
- unequal e- distribution
Induced dipole results when…
molecules are near a charge