Integumentary System Flashcards
What is the purpose of the Integumentary system?
Covers and protects underlying structures. Forms barrier against external world
What are the 6 functions of Integument (skin)?
- prevent desiccation
- reduce threat of injury
- help maintain body temperature
- excretion of water/salt/organic wastes
- sensory organ
- site of vitamin D synthesis and storage
Name the 3 organizations of skin
hint: -dermis
- epidermis
- dermis (corium)
- hypodermis
Name the functions and describe the epidermis
outermost layer, composed of keratinized stratified squamous epithelium. Is avascular.
Define and explain the Corium
dermis, includes blood vessels, glands and hair follicles. Composed of loose connective, smooth muscle, and dense fibroelastic. Dominant layer of skin, basememnt membrane. Dermal papillae
Define and describe the hypodermis
subcutaneous layer, mainly composed of adipose tissue. functions to be an insulator and mechanical shock absorber.
Name the four cells in the epidermis
- keratinocytes
- melanocytes
- langerhans
- merkel
What is the purpose of keratinocytes?
primary cell found in the epidermis, produces keratin. Constantly dividing on basement membrane and die as pushed up to surface, becoming sheets of keratin.
What is the purpose of melanocytes?
found in the basal layer of epidermis, octopus cell shape extension that reach keratinocytes. produced pigment melanin stored in melanosome granules that get released into interstitial space. Are absorbed by keratinocytes superficially from UV light exposure
Define Langerhan cells
macrophage specific to epidermis, originates from bone marrow and migrates to skin. Play an important role in stimulating aspects of immune system and phagocytizes microinvaders.
Define Merkel cells
located at epidermal-dermal junction. Found in small numbers and associated with sensory nerve endings thought to aid in touch sensation.
What are the 5 layers of the Epidermis?
- Stratum basale
- Stratum spinosum
- Stratum granulosum
- Stratnum lucidum
- Stratnum corneum
Describe the stratum basale
Deepest layer of epidermis. Consists of single row of keratinocytes, which are firmly attached to epithelial basement membrane. Includes small amounts of merkel cells and melanocytes.
Describe the stratum spinosum
Spiny layer, consists of many layers of keratinocytes held together by desmosomes. Keratinocytes also called prickles cells. Infrequent cell division. Abundant langerhans form web-like frame around keratinocytes
Describe the stratum granulosum
middle layer of skin, composed of 2-4 layers of flattened diamond shaped keratinocytes. Cytoplasm fills with keratohyaline granules.