integumentary system Flashcards
skin (the largest organ) and accessory structures of hair, nails, glands, muscles and nerves
integumentary system
medical specialty for integumentary system disorders
dermatology
superficial thinner portion epithelial tissue (top)
epidermis
deeper thicker portion connective tissue (middle)
dermis
not part of the skin below skin areolar tissues adipose tissues and storage depot of fat contains large vessels and contains lamellated corpuscles
hypodermis/ subcutaneous layer
pressure sensitive nerve endings in subcutaneous layer
lamellated (Pacinian) corpuscles
90% epidermal cells arrange layers produce protein keratin protects skin and body from heat, microbes, chemicals produce lamellar granules release water-repellent sealant.
keratinocyte
8% epidermal cells produce pigment melanin brown-black pigment determines skin color absorbs UV light shields nucleus & DNA
Melanocyte
small fraction (<2%) arise from red bone marrow migrate to epidermis participate in immune responses against microbes invading skin easily damage by UV light
Langerhans cells
least numerous (<1%) located in deepest layer contact flattened process of sensory neuron tactile detect different aspects of touch sensations
Merckel cells
(bottom) deepest layer of epidermis single row of cuboidal or columnar keratinocytes some cells are stem cells continually divide produce new keratinocytes
stratum basale
8-10 layers of many-sided keratinocytes some cells may retain ability to divide when prepared for microscope cells shrink & pull apart look like they have spines, spines are locations where tonofilaments insert into desmosomes
stratum spinosum
3-5 layers of flattened keratinocytes cells undergoing apoptosis
stratum granulosum
present only in fingertips, palms, soles 3-5 layers flattened clear dead keratinocytes large amounts of keratin and thickened plasma membranes
stratum lucidum
25-30 layers flattened dead keratinocytes continuously shed & replaced
stratum corneum
sloughing takes 4 weeks on average
stratum basale
superficial dermis 1/5 th of total thickness areolar CT with elastic fibers
papillary region of dermis
small projections of dermis increase surface area may contain capillary loops
dermal papillae
touch receptors
meissner corpuscles
warmth, coolness, pain, tickling, itching
free nerve endings