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PR2156 > Integumentary Diseases and Drugs > Flashcards

Integumentary Diseases and Drugs Flashcards

1
Q

Ketoconazole ( Nizoral)

A

controls itching, scaling associated with dandruff, antifungal (shampoo)

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1
Q

Tacrolimus

A

atopic dermatitis/perioral dermatitis/mild psoriasis, topical calcineurin inhibitor (ointment) [0.03% for 2 yrs and above = grp 4-5 TCS] [0.1% for 16 yrs and above = grp 4 TCS]

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2
Q

Pimecrolimus

A

atopic dermatitis/perioral dermatitis/mild psoriasis, topical calcineurin inhibitor (cream) [1% for 3 mths and above = grp 6 TCS]

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3
Q

Crisaborole

A

atopic dermatitis, topical phosphodiesterase 4 inhibitor [2% ointment]

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4
Q

Ruxolitinib (Not HSA approved)

A

atopic dermatitis, JAK inhibitor, tablet [short term use only] *max dose 60g/week or 100g/2 weeks

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5
Q

Topical corticosteroids (examples and classes in separate deck)

A

atopic dermatitis/mild-mod psoriasis, TCS (be careful for withdrawal symptoms) *if using class 1/2 high potency TCS–> maximum 2-4 weeks of usage (many cutaneous and systemic side effects)

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6
Q

Dupilumab

A

severe AD that does not respond to topical treatment, Biologic/IL-4/13 antagonist, SC injection

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7
Q

Cyclosporine (oral)

A

severe AD/severe psoriasis, immunosuppressant

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8
Q

Azathioprine (oral)

A

severe AD, immunosuppressant

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9
Q

Abrocitinib

A

severe AD that does not respond to topical treatment, biologics and other systemic drugs, JAK inhibitor

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10
Q

Upadacitinib

A

severe AD that does not respond to topical treatment, biologics and other systemic drugs, JAK inhibitor

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11
Q

Chlorpheniramine

A

secondary infections from AD, oral antihistamine

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12
Q

Flucloxacillin

A

secondary bacterial infections from AD (due to excoriated skin), antibiotic

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13
Q

Acyclovir

A

secondary viral infections from AD/ Herpes Labialis, antiviral

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14
Q

Hydrocortisone

A

AD/ACD/ICD, TCS

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15
Q

Clobetasone

A

ACD/ICD, TCS

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16
Q

Ivermectin (Oral)

A

Scabies, Anthelmintic

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17
Q

Isotretinoin (Oral)

A

severe AV/ acne conglobata, retinoic acid derivative that targets sebaceous glands. (teratogenic, dry eyes, sun-sensitivity [use of sunscreen], depression/suicidal]

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18
Q

Adapalene

A

AV, topical retinoid (1st choice therapy)

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19
Q

Tretinoin

A

AV, topical retinoid (teratogenic and sun-sensitivity)

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20
Q

Tarazotene

A

AV, topical retinoid (teratogenic and sun-sensitivity)

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21
Q

Benzoyl Peroxide

A

AV, antimicrobial/anti-inflammatory/anti-comedonal (will cause erythema and xerosis but continue usage) (usually used in combined therapy with retinoids/oral antibiotics)

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22
Q

salicylic acid

A

AV/mild-mod psoriasis, exfoliant and has keratolytic propertis (not very safe and efficaceous for AV) *cannot be used with phototherapy and Vit D analogues

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23
Q

Azelaic acid

A

mild-mod AV, comolytic/antibacterial/ anti-inflammatory agent

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24
Clindamycin
AV, topical antibiotic (not recommended for mono-therapy due to possible antibiotic resistance) (used tgt with Benzoyl peroxide)
25
erythromycin (oral)
AV, oral antibiotics (safe in pregnant women)
26
tetracycline
AV, oral antibiotics (teratogenic, sun-sensitive and should not be used alone due to possible antibiotic resistance) (used with concurrent topical therapy)
27
doxycycline
AV, oral antibiotics (teratogenic, sun-sensitive and should not be used alone due to possible antibiotic resistance) (used with concurrent topical therapy)
28
minocycline
AV, oral antibiotics (teratogenic, sun-sensitive and should not be used alone due to possible antibiotic resistance) (used with concurrent topical therapy)
29
cyproterone acetate with ethinyl estradiol
for long term AV in women, hormonal therapy with oral contraceptive (anti-androgenic properties)
30
erythromycin (topical)
perioral dermatitis, topical antibiotic
31
oxymetazoline (topical)
rosacea, alpha adrenergic agonist
32
brimonidine (topical)
rosacea, alpha adrenergic agonist
33
mupirocin
Impetigo, topical antibiotic (kills methicillin resistant S.aureus)
34
retapamulin
Impetigo, topical antibiotic
35
topical fusidic acid (Fucidin)
Impetigo, topical antibiotic (increasing resistance to S.aureus)
36
Ozenoxacin
Impetigo, topical antibiotic/quinolone
37
Miconazole (topical)
angular cheilitis/tinea infections not including tinea capitis, antifungal
38
Kenacomb: neomycin, gramicidin, nystatin, triamcinolone acetonide
angular cheilitis, hybrid antifungal and antibacterial
39
Trifarotene
truncal acne, topical retinoid
40
Itraconazole (oral)
tinea infections including tinea capitis, oral antifungal
41
Fluconazole (oral)
tinea infections including tinea capitis, oral antifungal
42
Terbinafine (oral)
tinea infections including tinea capitis/gold standard treatment for onychomycosis, oral antifungal (effective in preventing recurrence)
43
Griseofulvin (oral)
tinea capitis caused by M.audouinii, oral antifungal
44
Ketoconazole (oral)/(topical)
tinea infections/seborrheic dermatitis(topical only), antifungal
45
clotrimazole (topical)
tinea infections not including tinea capitis, topical antifungal
46
Isoconazole (topical)
tinea infections not including tinea capitis, topical antifungal
47
sertaconazole (topical)
tinea infections not including tinea capitis, topical antifungal
48
Itraconazole (pulse therapy)
Onychomycosis, anti fungal
49
Amorolfine
Onychomycosis, anti fungal
50
Ciclosporax (not HSA approved)
Onychomycosis, hydroxypyridone derivative
51
Tavaborole (not HSA approved)
Onychomycosis, anti fungal
52
Calcitriol
mild-mod psoriasis, Vit D analogue (inactivated by salicylic acid)
53
Calcipotriol
mild-mod psoriasis, Vit D analogue (inactivated by salicylic acid)
54
tacaltriol
mild-mod psoriasis, Vit D analogue (inactivated by salicylic acid)
55
Coal tar
mild-mod psoriasis
56
PUVA/UVB phototherapy
moderate psoriasis
57
acitretin
mod-severe psoriasis, oral retinoid (teratogenic and need to avoid ethanol)
58
apremilast
mod-severe psoriasis, oral phosphodiesterase 4 inhibitor
59
methotrexate
severe AD/mod-severe psoriasis, oral immunosuppressant
60
etanercept
mod-severe psoriasis, biologic (TNF-alpha inhibitor)
61
infliximab
mod-severe psoriasis, biologic (TNF-alpha inhibitor)
62
adalimumab
mod-severe psoriasis, biologic (TNF-alpha inhibitor)
63
certolizumab
mod-severe psoriasis, biologic (TNF-alpha inhibitor)
64
secukinumab
mod-severe psoriasis, biologic (IL-17 inhibitor)
65
ixekizumab
mod-severe psoriasis, biologic (IL-17 inhibitor)
66
brodalumab
mod-severe psoriasis, biologic (IL-17 inhibitor)
67
guselekumab
mod-severe psoriasis, biologic (IL-23 inhibitor)
68
tildrakizumab
mod-severe psoriasis, biologic (IL-23 inhibitor)
69
risankizumab
mod-severe psoriasis, biologic (IL-23 inhibitor)
70
tofacitinib
severe psoriasis, JAK inhibitor
71
minoxidil
androgenetic alopecia/alopecia areata, topical skin product
72
finasteride
androgenetic alopecia, 5-alpha reductase inhibitor (for men only)
73
Triamcinolone acetonide injection
alopecia areata, corticosteroid (injected intradermally)
74
Octinoxate
organic filter in sunscreen, Cinnamate (UVB)
75
Octocrylene
organic filter in sunscreen, (UVB)
76
Oxybenzone
organic filter in sunscreen, benzophenone (UVB, UVA2)
77
Avobenzone
organic filter in sunscreen, benzophenone (UVA1)
78
ZnO
inorganic filter in sunscreen
79
TiO2
inorganic filter in sunscreen

PR2156 (4 decks)

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