Integumentary Flashcards
Surface area of skin in adults
2 sq m
Average thickness of the skin
2 mm
Stress response character
Forms calluses for extra protection
Outer layer
Epidermis
Inner layer
Dermis
Epidermis
Epithelial and a vascular receiving nutrients from diffusion from dermis
Dermis
Connective and vascularized
Hypodermis
Subcutaneous layer that is deep to dermis and contains adipose fat and large vessels the supply skin
Epidermis is composed of
Keratinized stratified squamous epithelium and 4 cell types
4 cell types
Keratinocytes
Melanocytes
Langerhans cells
Merkel cells
Keratinocytes
90%
Arranged in 4 to 5 layers
Keratin is lamellar granules
Melanocytes
8% or so
Ectodermal in origin and produce melanin
Very susceptible to uv light
Melanin provides some protection
Langerhans cells
Arise from red marrow and migrate to epidermis
Few in number
Important in immune response
Susceptible to uv light
Merkel cells
Lie in deepest layers
Associate with sensory neurons in touch sensations
Merkels disk
Stratum lucidum
Only present in thick skin
Stratum corneum
Horny, tough, flat, dead Keratinized cells
Stratum granulosum
Dying cells like “pepper flakes” or granules in them
Stratton spinosum
Cells have spiny processes
Stratum basale
Cells are actively growing