Integrative Flashcards
5 List 3 markers of testicular tumours
aFP
hCG
LDH
5 What 2 types of drugs would you use to manage male lower urinary tract symptoms ?
Alpha blockers (rapid relief) 5α-Reductase Inhibitors (slower symptom relief but slows progressio reduces risk of retention)
5 What examination/s would you do for a male patient with LUTS (lower urinary tract symptoms)?
Examine penis
DRE
5 What is the incidence of phimosis?
1% in adult non-circumcised population
More so in childhood & adolescence (physiological)
5 List 8 sequelae of phimosis
Hygiene issues incl inc risk STIs Pain on intercourse, splitting / bleeding Balanitis Posthitis (inflamed foreskin / prepuce) Balanitis Xerotica Obliterans Paraphimosis Urinary retention Penile cancer
5 What are the 3 commonest causes of paraphimosis?
Phimosis
Catheterisation
Penile cancer
5 What are the 2 main risk factors for squamous cell carcinoma of the penis?
Phimosis (due to poor hygiene and smegma build up)
HPV 16 and 18
5 Besides religious choice what are the main indications for pediatric circumcision ?
Recurrent balanitis and UTIs
5 List 5 key indications for circumcision in adults
– Recurrent balanitis – Phimosis – Recurrent paraphimosis – Balanitis xerotica obliterans – Penile Cancer
5 What cause should you always consider in acute scrotal pain?
Testicular torsion
5 What is the typical history in testicular torsion?
Young man, under 30
Sudden onset of unilateral scrotal pain with nausea but no associated lower urinary tract symptoms.
5 How would you manage a patient with suspected testicular torsion?
Examination and refer to urology for emergency scrotal exploration
5 What findings on examination would help confirm a diagnosis of testicular torsion?
Very tender testis, lying high in scrotum with horizontal lie
5 What’s the most common cause of epididymo-orchitis in middle aged men?
UTI (esp E.coli)
5 Why is it important to examine the skin of the whole scrotal and perineal area in cases of epididymo-orchitis?
In case of Fournier’s Gangrene - necrotic area of scrotal skin.
Although rare has a high mortality rate
5 Why is it more worrying if a palpable scrotal lump is within the body of the testis?
May be a testicular tumour
5 What is the differential diagnosis for a painful and tender scrotal lump?
Epididymitis
Epididymo-orchitis
Strangulated inguino-scrotal hernia (this is an emergency)
5 In what age range are germ cell testicular tumours most common?
<45 year olds (in older men tumour may be lymphoma)
5 How does a hydrocele form?
imbalance of fluid production and
resorption between tunica albuginea and tunica vaginalis
5 What would be the typical history of a varicocele?
History of dull ache in scrotal area in evenings. On examination L sided non-tender scrotal swelling with “bag of worms” texture above testis.
5 What is the treatment for a testicular tumour?
Inguinal orchidectomy
5 When would a radiological embolisation be indicated for a varicocele?
If pt symptomatic, infertile, or if adolescent and growth of testis affected
(otherwise reassurance)
5 What range of residual volume of urine would suggest that a case of urinary retention has an acute cause?
<1000ml
acute on chronic >1000ml
5 What are the 2 main treatments for acute-on-chronic urinary retention
Long term catheter
Surgery
(NB trial w/o catheter usually unsuccessful and no point if associated kidney damage)
5 What is the main cause of nocturnal enuresis in older men?
Chronic retention w/ overflow incontinence
5 What are the main type of receptors that mediate sympathetic smooth muscle tone of the bladder?
Alpha 1 adrenoreceptors
5 What are the 3 main lifestyle interventions for managment of BPH?
- Reduce caffeine intake
- Avoid fizzy drinks
- Avoid drinking more than 2.5L day
5 How do 5α-Reductase Inhibitors work?
Shrink prostate by depriving it of androgens
5 What is the standard surgical treatment for BPH?
Transurethral resection of prostate (TURP)
5 If there is a scrotal lump in the body of the testis, what cause is it vital to investigate for?
Testicular cancer
5 What are the 6 main physical causes of erectile dysfunction?
Diabetes Atherosclerosis incl smoking Regular heavy drinking Side effects of prescribed drugs (esp those for high blood pressure, heart disease, depression, peptic ulcers and cancer) Prostate gland surgery Spinal cord injury