Integration Research Cases Flashcards
1
Q
Pathos of RA
A
- antigen triggers abnormal Igg response
- IgG AND RF Combine to form an immune complex that deposits on synovial membranes and superficial articular cartilage in joints
- complement and inflammatory response is triggered in those deposit locations
- neutrophils are summoned to the inflammation cites
- they release proteolytic enzymes that eat the articular cartilage which results in the thickening of synovial lining
2
Q
Pathos for Constipation
A
- ignoring need to defecate leads to muscle and mucosa of rectal area to become insensitive to presence of feces
- prolonged retention of feces dries it up because of water absorption, which makes it hard and dry, which makes excretion more difficult
3
Q
Pathos of Anemia
A
- iron deficiency anemia is a caused by insufficient iron intake, which results in a deficiency of hemoglobin synthesis
- thalassemia involves inadequate hemoglobin synthesis, which results in decreased erythrocyte production. Thalassemia is caused by an absent or lacking globulin protein. Alpha or beta globulin which corresponds to alpha or beta thalassemia
4
Q
Pathos of Osteoporosis
A
- bone reabsorption is faster than bone creation
- results in spontaneous fractures, breaks, and kyphosis
5
Q
Pathos of Urinary Incontinence
A
- stress ui is increase in inside abdominal pressure which causes involuntary release of urine. can happen during lifting, laughing, coughing, straining
- functional ui is loss of urine because of patient mobility problems or environmental factors
6
Q
Pathos of Chronic Renal Failure
A
- progressive decline in kidney function due to irreversible damage done to glomeruli or renal tubules
- could be caused by cardiovascular issues that stop blood flow to the kidneys. which impairs fluid retention and waste removal, that leads to chronic renal failure
7
Q
Pathos of Moderate Vascular Dementia
A
- cardiovascular condition will stop blood and oxygen flow to the brain, which results in a stroke/strokes that lead to vascular dementia
8
Q
Pathos of Chronic Bronchitis
A
- cascading inflammatory response of the airways
- excess mucus production due to increased mucus secreting goblet cells and enlarged submucosal glands, that respond to smoke or other inhalants. Could also be the result of cilia dysfunction or inflammatory mediators that stimulate mucus production
9
Q
Pathos of CAD
A
- endothelial lining gets injured
- lipids accumulate and migrate into smooth muscle cells
- collagen covers the fatty streak, narrows vessel lumen
- reduces blood floor and gives opportunity for fissure development
- plaque ruptures, creates a thrombus formation, further narrows or blocks off vessel
10
Q
Risk Factors for RA
A
- Genetic Predisposition for RF
- Indigenous population and women are at higher risk
11
Q
Risk Factors for Constipation
A
- not enough fiber in your diet
- not enough fluid intake
12
Q
Risk Factors for Anemia
A
-indigenous people are at risk for iron-deficiency anemia because of lifestyle and social determinants of health
- thalassemia occurs more in people with north african, east asian, or mediterranean origin
13
Q
Risk Factors for Osteoporosis
A
- Calcium and Vitamin D deficiency
- Weak bone formation during childhood
14
Q
Risk Factors for UI
A
- women are more affected than men
- people with CNS or Bladder disorders are at risk of urge incontinence
15
Q
Risk Factors for Chronic Renal Failure
A
- Canadians who are also Indigenous, Asian, Pacific Islanders, African/Caribbean, and Latin American
- Patients with diabetes, htn, vascular disease, autoimmune disease, low valued GFR, and edema
16
Q
Risk Factors for Moderate Vascular Dementia
A
- HTN and CAD
- Older Age
17
Q
Risk Factors for Chronic Bronchitis
A
- smoking
- aging which results in structural change in the lungs that lose elastic recoil
18
Q
Risk Factors for CAD
A
- Genetic Predisposition, which makes it more likely for plaque formation in coronary arteries
- Physical Inactivity
19
Q
SnS of RA
A
- symmetrical joint pain, ache, tenderness, erythema, enlargement, deformities, stiffness, swelling, heat
- muscle contraction, weakness, atrophy, and difficulty walking