Integ Flashcards
The process of scar tissue formation
Fibrosis
Scar remain within the boundaries of the original wound
Hypertrophic scar
Scars that extends beyond tye boundaries of the originsl wound into normsl surrounding tissues
Keloid scars
Four phases of deep wound cleaning
Inflammatory phase, migratory phase, proliferative phase, maturation phase
Tissue filling the wound
Granulation tissue
The edges of wound involve only slight damage to superficial epidermal cells
Epidermal wound healing
2 types of skin wound healing
Epidermal wound healing, deep wound cleaning
Caused by staphylococcus aureus; characterized by small blisters containing pus that easily rupture and forms a yellowish crust
Impetigo
Disorder of hair follicles and sebaceous glands
Acne
Necrosis of the skin due to tissue compression & reduced circulation
Decubitus Ulcers / bed sores / pressure sores
Fluid-filled areas in the skin that develop when tissues are damaged
Bullae
Caused by increased mitosis in stratum basale, abnormal keratinization and elongation of dermal papillae tward the skin surface producing thicker than normal skin
Psoriasis
Inflammatory conditions of the skin
Eczema & dermatitis
Fungal infection affecting the keratinized portion of the skin, hair, nails
Ringworm
Chicken pox, measels, warts
Viral infections
Congenital disorder of the capillary of the dermis
Birthmarks
Development of patches of white skin
Vitiligo
Rare form of 2% of all skin cancers most prevalent life-threatening cancer in young women metastasize rapidly and can kill a person within moths of diagnosis
Malignant melanoma
20% of all skin cancers arise from squamous celld of the epidermis and have a variable tendency to metastasize
Squamous cell carcinoma
Most frequent 78% of all skin cancers tumors arise from cells in the stratum basale of the epidermis and rarely metastasize
3 types of skin cancer
Basal cell carcinoma, squamous cell carcinoma, malignant melanoma
Idication of yellowish discoloration
Liver problems
Bluish lips/skin color
Hypoxia / oxygen defficiency
Largest organ outside the body
Skin
Surface area of the skin
Approximately 2 sq. m
The skin weighs…
Appeoximately 6kg (4-5) and about 7% of the body weight
8 function of the skin
Protection, thermoregulation, absorption, immunizaty, sensation, excretion, blood reservoir, synthesis of vitamin D
Protects underlying tissues
Keratin
Resist invasion by microbes
Interlocked keratinocytes
Released by the lamellar granules retard evaporation of water
Lipids
Protects the skin and the hair from dying
Oilu sebum
Retards the growth of microbes
Perspiration (acidic pH)
Provides protection against UV rays
Melanin
2 types of sensation that arise in the skin
Tactile, thermal
Receptors in the epidermis and dermis
Free nerve endings corpuscle, pacinian corpuscle, merkel’s corpuscle
Active form of vitamin D
Calcitriol
Liberating sweat at its surface and by adjusting the flow of blood in the dermis
Thermoregulation
Sweating, removal of heat, water and other substances like salts CO2, lrganic molecules from the breakdown of CHON (ammonia, urea)
Excretion
Oily material that lubricates the skin and hair
Sebum
Recognize and process some microbe
Langerhans cells (stratum spinosum)
Skin house 1/3 of blood vessels supplying the body
Blood reservoir
Section of the skin
Epidermis, dermis, hypodermis or subcutaneous tissue
Dermatology came from the word
Dermat= skin, ology=study of
Branch of medicine the specializes in diagnosing and treating skin disorders
Dermatology
The skin generates every
2 weeks
Parts of epidermis
Stratum corneum
Stratum lucidum
Stratum granulosum
Stratum spinosum
Stratum basale
Layers of the dermis
Papillary layer, reticular layer
Forms a covering of the entire body surface; flat, thick layer kd deadcells/keratinocytes; continually sheds off/ desquamates
Stratum corneum
Most prominent in palms, soles; flat CLEAR layer of deadcells which contain ELEIDIN
Stratum lucidum
Transitional subtance between keratin and keratohyalin
Eleidin
Where some new cells are formed & pushed to the surface
Stratum germinativum
A developmental process that newly form cells in the stratum basale undergo as they are being pushed to the surface
Keratinization
A protein hormone that stimulates growth of epidermal cells
Epidermal growth factor (EGF)
What protein gives the skin its structural strength
Collagen
Sub-epithelial layer; consists of papillae that extend into the epidermis forming fingerprints and footprints; contain blood vessels
Papillary layer
Depper layer; netlike layer of collagen & elastic fibers (strength, extensibility, elasticity)
Reticular layer
Visible red/silvery streaks on the surface of the skin or small tears in the dermis due to extreme stretching
Striae or stretch marks
Epidermal ridges or grooves + sweat=
Fingerprints and footprints
Layer of the skin that contains fat
Hypodermis
3 pigments
Melanin
Carotene
Hemoglobin
Brown to black
Melanin
Yellow to orange
Carotene
Factors affecting melanin production
Genetic, hormones, exposure to sunlight
How is melanin synthesized?
Exposure to UV lights, increased activity of the melanosomes, increased melanin production, tanned appearance of the skin, protection
Skin derivative
Hair, nails, receptors, glands
The color of the hair is due to
Melanin
Gray hair is due to
Decline in tyrosinase
Superficial portion of the hair
Shaft
Portiion that penetrates the dermis or SC layer
Root
Surround the root of the hair; made of external and internal root sheath
Hair follicle
At the base of each hair follicle; houses the papilla of the hair and contains the matrix
Bulb
Contracts/pulls the hair shaft/ goose bumps/ gooseflesh
Arrector pili muscle
Forms the central core; contains soft keratin; pigment granules and air spaces
Medulla
Thickest layer, major part of the shaft; hard portion surrounding the medulla, containing pigment granules im dark hair but mostly air in gray or white hair
Cortex
Made up of thin squamous cells, mostly heavily keratinized, that overlap to create a scale-like appearance, their free edges pointing towag the end of the hair
Cuticle
Types of glands
Sebaceous (oil glands), sweat glands ( suderiferous)
Simple, branched acinar glands, connected to hair follicles
Sebaceous/ oil glands
Two types of suderiferous glands
Eccrine/merocrine, apocrine
Produces sweat
Merocrine glands
Commonly known as cold sweat
Apocrine
Superficial skin infection; caused by staphylococcus aureus; small blisters with pus
Impetigo
Affection of the hair follicles & sebaceous glands
Acne
Necrosis (death) of skin tissue
Decubitus ulcer
Fluid-filled areas of the skin
Bullae
Skin disease marked by scaly patches
Psoriasis
Inflammatory condition of the skin
Dermatitis
Fungal infection that affects the keratinized portion of the skin
Ringworm
Viral infection with fluid-filled vesicles
Chickenpox
Viral infection, characterized by unevaluated lesions/redness (macule)
Measles
Cogenital disorders affecting the capillaries of fhe skin
Birthmark
White irregular patches
Vitiligo
First lesions to appear on the skin
Primary lesions
Redness and inflammation of the skin & mucous membrane
Ertythema
Discolorations of irregular shape
Patches
Small circumscribed solid elevation
Papule
Circumscribed, thin translucent lesion, fluid-filled, blood-filled
Vesicle
Larger than vesicles
Bullae
Vesicle/bullae filled with pus
Pustule
Larger than papule
Nodule
Inherited inability of an individual to produce melanin
Albinism
Modified sweat glands in the external ear, producing waxy secretions known as cerumen or earwax
Ceruminous glands