Insulins Flashcards

1
Q

glipizide (Glucotrol)
glyburide (Glynase)
glimepiride (Amaryl)

A

2nd generation sulfonylureas

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2
Q

glipizide (Glucotrol)
glyburide (Glynase)
glimepiride (Amaryl)
ACTION

A

Works to increase output of insulin by beta cells in pancreas

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3
Q

glipizide (Glucotrol)
glyburide (Glynase)
glimepiride (Amaryl)
Nx Implications

A

Best taken 30 min prior to meal
Main potential side effects: hypoglycemia with delayed or skipped meals or alcohol
Use cautiously in elderly

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4
Q

metformin Glucophage

A

Biguanide

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5
Q

metformin Glucophage

ACTION

A

Decrease liver output of sugar

Increase peripheral insulin sensitivity

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6
Q

metformin Glucophage

Nx Implication

A

Kidney surveillance testing required (monitor serum creatinine)
Contraindicated if pt has CHG, alcohol abuse, metabolic acidosis, liver or kidney disease, or > 80 years old
Main potential side effects: GI distress/diarrhea, lactic acidosis
Take with food
Discontinue after OR, dye studies for 48 hours or until kidney function normal

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7
Q

Insulin

Nx Implications

A

Monitor blood sugar level

When mixing, draw rapid acting first (clear before cloudy)

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8
Q

lispro Humalog
aspart Novalog
CLASS

A

Very rapid acting

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9
Q

lispro Humalog
aspart Novalog
ACTION

A

Onset: 10 min
Peak: 1hr
Duration: 3-4hrs

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10
Q

lispro Humalog
aspart Novalog
Nx Implication

A

Clear solution

Give 15 min prior to meal

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11
Q

Regular R

CLASS

A

Short (rapid) acting

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12
Q

Regular R

ACTION

A

Onset: 30 min
Peak: 3-5hrs
Duration: 6-10hrs

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13
Q

Regular R

Nx Implication

A

Clear solution

Give 30 min prior to meal

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14
Q

NPH
Lente
CLASS

A

Intermediate acting

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15
Q

NPH
Lente
ACTION

A

Onset: 1hr
Peak: 6-12hrs
Duration: 20-24hrs

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16
Q

NPH
Lente
Nx Implication

A

Cloudy solution

Rotate prior to use

17
Q

glargine Lantus

CLASS

A

Long acting

18
Q

glargine Lantus

ACTION

A

Onset: 1hr
Peak: No peak
Duration: 24hrs

19
Q

glargine Lantus

Nx Implication

A

Clear solution

Do not mix with others

20
Q

detemir Levemir

CLASS

A

Long acting

21
Q

detemir Levemir

ACTION

A

Onset: 3-4hrs
Peak: No peak
Duration: 24hrs

22
Q

detemir Levemir

Nx Implications

A

Clear solution

Do not mix with others