Insulins Flashcards
glipizide (Glucotrol)
glyburide (Glynase)
glimepiride (Amaryl)
2nd generation sulfonylureas
glipizide (Glucotrol)
glyburide (Glynase)
glimepiride (Amaryl)
ACTION
Works to increase output of insulin by beta cells in pancreas
glipizide (Glucotrol)
glyburide (Glynase)
glimepiride (Amaryl)
Nx Implications
Best taken 30 min prior to meal
Main potential side effects: hypoglycemia with delayed or skipped meals or alcohol
Use cautiously in elderly
metformin Glucophage
Biguanide
metformin Glucophage
ACTION
Decrease liver output of sugar
Increase peripheral insulin sensitivity
metformin Glucophage
Nx Implication
Kidney surveillance testing required (monitor serum creatinine)
Contraindicated if pt has CHG, alcohol abuse, metabolic acidosis, liver or kidney disease, or > 80 years old
Main potential side effects: GI distress/diarrhea, lactic acidosis
Take with food
Discontinue after OR, dye studies for 48 hours or until kidney function normal
Insulin
Nx Implications
Monitor blood sugar level
When mixing, draw rapid acting first (clear before cloudy)
lispro Humalog
aspart Novalog
CLASS
Very rapid acting
lispro Humalog
aspart Novalog
ACTION
Onset: 10 min
Peak: 1hr
Duration: 3-4hrs
lispro Humalog
aspart Novalog
Nx Implication
Clear solution
Give 15 min prior to meal
Regular R
CLASS
Short (rapid) acting
Regular R
ACTION
Onset: 30 min
Peak: 3-5hrs
Duration: 6-10hrs
Regular R
Nx Implication
Clear solution
Give 30 min prior to meal
NPH
Lente
CLASS
Intermediate acting
NPH
Lente
ACTION
Onset: 1hr
Peak: 6-12hrs
Duration: 20-24hrs