Insomnia Flashcards
What are the symptoms of insomnia ?
- difficulty initiating sleep, difficulty maintaining sleep
- early morning awaking, poor sleep quality
What type of insomnia there are ?
Transient Insomnia
Short-term insomnia
Chronic insomnia
How to treat transient insomnia ?
Better to give short acting hypnotic, give only one or two doses
How to treat short-term insomnia ?
usually related to emotional problem or serious medical illness. Short acting hypnotic is usually appropriate, give for no more than three weeks, give intermittently and omit some doses
Name short acting hypnotics ? ( z- drugs ) CD4 part 1
zopiclone ( taste disturbance )
zolpidem, ( GI disturbance, leave 8 hours before driving )
zaleplon ( shortest acting )
Little hangover effect
How long should Z drugs be used ?
Zaleplon only max two weeks, others max four weeks
Name long acting benzodiazepines?
Nitrazepam
Diazepam
flurazepam
Name shorter acting benzodiazepines ?
temazepam (CD3) lorazepam loprazolam loretazepam oxazepam
How does Z-drugs work ?
act on benzodiazepine site of GABA a receptors to facilitate and enhance the binding of GABA to GABA a receptors.
Side effects of Z-drugs ?
paradoxical effects
daytime sleepiness
How quick tolerance develops with Z- drugs ?
in 3 to 14 days of continues use; take only when needed