INR-Food Interactions

Question 1

Asparagus results in INR (decreasing/increasing).

Answer 1

Decreasing (due to Vitamin K)

Question 2

Avocado results in INR (decreasing/increasing).

Answer 2

Decreasing (due to Vitamin K)

Question 3

Broccoli results in INR (decreasing/increasing).

Answer 3

Decreasing (due to Vitamin K)

Question 4

Brussel Sprouts result in INR (decreasing/increasing).

Answer 4

Decreasing (due to Vitamin K)

Question 5

Cabbage results in INR (decreasing/increasing).

Answer 5

Decreasing (due to Vitamin K)

Question 6

Kale results in INR (decreasing/increasing).

Answer 6

Decreasing (due to Vitamin K)

Question 7

Peas results in INR (decreasing/increasing).

Answer 7

Decreasing (due to Vitamin K)

Question 8

Spinach results in INR (decreasing/increasing).

Answer 8

Decreasing (due to Vitamin K)

Question 9

Blueberries result in INR (decreasing/increasing).

Answer 9

Decreasing (due to Vitamin K)

Question 10

Pineapple results in INR (decreasing/increasing).

Answer 10

Increasing (due to Bromelain)

Question 11

Blackberries result in INR (decreasing/increasing).

Answer 11

Decreasing (due to Vitamin K)

Question 12

Grapes result in INR (decreasing/increasing).

Answer 12

Decreasing (due to Vitamin K)

Question 13

Cashews result in INR (decreasing/increasing).

Answer 13

Decreasing (due to Vitamin K)

Question 14

Pistachios result in INR (decreasing/increasing).

Answer 14

Decreasing (due to Vitamin K)

Question 15

Cilantro results in INR (decreasing/increasing).

Answer 15

Decreasing (due to Vitamin K)

Question 16

Dill Pickles results in INR (decreasing/increasing).

Answer 16

Decreasing (due to Vitamin K)

Question 17

Lettuce [NOT ICEBERG] results in INR (decreasing/increasing).

Answer 17

Decreasing (due to Vitamin K)

Question 18

Mayonnaise results in INR (decreasing/increasing).

Answer 18

Decreasing (due to Vitamin K)

Question 19

Certain nutritional replacement shakes may result in INR (decreasing/increasing).

Answer 19

Decreasing (due to Vitamin K)

Question 20

Cranberries result in INR (decreasing/increasing).

Answer 20

Uncertain! Conflicting literature suggests there may not be a clinically significant connection (literature suggests only a LARGE volume may affect INR)

Question 21

Grapefruit results in INR (decreasing/increasing).

Answer 21

Uncertain! Conflicting literature suggests there may not be a clinically significant connection, however, we should caution patients all the same

Question 22

Mango results in INR (decreasing/increasing).

Answer 22

Increasing (due to mild antiplatelet properties that augment Warfarin’s effects)

Question 23

Papaya results in INR (decreasing/increasing).

Answer 23

Increasing (due to papain in UNRIPE fruit which may contribute to gastrointestinal bleeding)

Question 24

Pomegranate results in INR (decreasing/increasing).

Answer 24

Increasing (*WEAK data to support this)

Question 25

Garlic results in INR (decreasing/increasing).

Answer 25

Increasing (potentiates bleeding via aggregation of platelet inhibition)

Question 26

Ginger/Ginger Ale results in INR (decreasing/increasing).

Answer 26

Increasing (potentiates bleeding via aggregation of platelet inhibition)

Question 27

Black Licorice results in INR (decreasing/increasing).

Answer 27

Uncertain! (Some sources say it potentiates bleeding via CYP3A4 inhibition, others say it has coumarins and should lower INR by inactivating warfarin)

Question 28

Dark Chocolate results in INR (decreasing/increasing).

Answer 28

Increasing (potentiates anticlotting activity via flavonol)

Question 29

Alcohol results in INR (decreasing/increasing).

Answer 29

VARIES. Increases acutely, but lowers chronically due to liver enzyme expression

Question 30

Turmeric results in INR (decreasing/increasing).

Answer 30

Increasing (some anticoagulant/blood thinning properties via curcumin)