INORGANIC COMPONENT Flashcards
• The typical salivary pH of an adult is between
6-7.4
what movement stimulated saliva production which allows buffering to take place to restore pH
MASTICATION
higher the sucrose conc leads to a
fall in pH
urea.. the rate at which pH was restored
increased
increased salivary flow rate leads to an
increased salivary buffering capacity
bicarbonate ions
-produced by striated epithelium of the secretory ducts and the parotid gland
is bicarbonate ions affected by the metabolic activity
yes
bicarbonate ions acts as a
buffer as pKA value is 6.1
at ph6.1 there are equal concentrations of carbonic acid and carbonate ions
as the salivary pH falls, the .. reaction is favoured
forward
flow rate increase, bicarbonate ions
increases
potassium and sodium ions are
counter ions that preserve electrical neutrality
what direction is sodium pumped as it passes along the intercalated duct of the salivary glad
- actively pumped OUT
- via the sodium-potassium pumps
low salivary rate results in ( affect on Na plus)
low Na + concentration
- so in duct for a longer period
- more Na + will be pumped out of the fluid
- so lower concentration
another possible reason for increased na plus concentration
damage of the ductal cells
as salivary flow rate increases, the potassium concentrations in the saliva
remain constant
increased flow rate affect on mg ions
low
compare conc of calcium ions in saliva compared to magnesium ion
- higher levels of calcium
role of calcium ions
- essential in remineralisation and prevent mineral dissolution
affect of flow rate on calcium ions
high flow rate, ca2 plus remains relatively constant
how does mg concentrations in saliva change as flow rate increases
decrease
phosphate ions
act as a buffer in unstimulated saliva
another function of phosphate ions
-important in the maintenance of ionic product for hydroxyapatite - inhibit dissolution and crucial for remineralisations
affect of flow rate on inorganic phosphate ios
high flow rate, low phosphate conc
-as phosphate is actively added to the secretion as it passes through the duct so a faster transit time will results in less phosphate being added
why does an increased flow rate result in a more alkaline PH
- due to an increased conc of bicarbonate ions
