Inorganic Chemistry Flashcards
Who discovered the triads?
JW Dobereiner
Who discovered periods?
John Newlands
Who discovered atomic mass/weight?
Dmitri Mendeleev & Mayer
Who discovered atomic number?
Henry Mosely
Father of modern periodic table
Dmitri Mendeleev
Created the modern periodic table
Henry Mosely
Every 8th element has similar physicochemical properties when arranged according to increasing atomic weight.
Law of Octaves
Elements (atomic number 1-20) with <8 electron “react” to achieve 8 electron (stable)
Octet Rule
1st most abundant element
O2
2nd most abundant element
Si
Most abundant metal
Al
Most abundant air gas
N2
Most abundant noble gas
Ar
Least abundant noble gas
Kr, Xe
Most abundant intracellular cation
K
Most abundant extracellular cation
Na
Most abundant intracellular anion
Phosphate
Most abundant extracellular anion
Chloride
2nd most abundant intracellular cation
Mg
2nd most abundant extracellular cation
Ca
2nd most abundant intracellular anion
Sulphate
2nd most abundant extracellular anion
Biphosphate
Most important physiological buffer system
Bicarbonate/HCO3-
CO2 (acidic)
Respiratory
HCO3 (basic)
Metabolic
DOC of metabolic acidosis
NaHCO3
What vitamins is in Fe?
Vitamin C
What vitamins is in Ca?
Vitamin D
What vitamins is in Se?
Vitamin E
Phlogisticated air
N2
Dephlogisticated air
O2
Black Cylinder
N2
Blue cylinder
NO2
Blue bottle
Mg(OH)2
Green Cylinder
O2
Dark green
Argon
Grey
CO2
Brown
Helium
Red
H2
Maroon
Acetylene
Yellow
Cl2
Coated with petroleum or under oil
Li
Highly resistant borosilicate (Pyrex, Borosil)
Type 1
Decrease coefficient of expansion
Boron
General Soda Lime Glass
Type 4
Treated Soda Lime Glass
Type 2
Soda Lime Glass
Type 3
Powder glass test
Type 1&3
Water attack test
Type 2
The loss or extraction of certain materials from a carrier into a liquid
Leaching
It involves the removal of drug content from the product by the packaging material
Sorption
Brown/Amber light - resistant
K
Glass etching
HF
Increase refractive index
Pb
Masks blue-green color Fe usually present in glass
MnO2
Selectively absorb light of certain wavelengths
Rare earths
Red
Se
movement disorder (tremors)
Hypokalemia
Nephrogenic DI (polyuria)
Hyponatremia
Deficiency of K
Hypokalemia
Toxicity of K
Hyperkalemia
Toxicity of Cu
Wilson’s disease
Tx of Wilson’s disease
Penicillamine (Cuprimine®)
Toxicity of Ag
Argyria
Toxicity of Ag
Argyria
Tx of Argyria
NaCl (NSS)
Toxicity of Gold
Dermatitis and Glossitis
Defective bone minerlizat
Rickets/bowed legs
Defective bone resorption
Osteoporosis
Toxicity of Calcium
Hypercalcemia
Tx of hypercalcemia
Ca EDTA
Toxicity of Barium
Baritosis (benign pneumoconiosis)
Tx of baritosis
MgSO4 —> BaSO4 (non absorbable)
Deficiency of Zn
Parakeratosis (scaly, thickened & inflamed skin), impaired immunity
Metal fume fever
ZnO
Tx of parakeratosis and metabolic acidosis
NaHCO3
Toxicity of Cd
Itai-Itai Disease
Tx of Itai-Itai Disease
Ca EDTA - immediately given after exposure
Mgt of Itai-Itai Disease
Palliative therapy
Neurotoxic of Hg
Minamata disease, Pink disease (acrodynia in children), Mad Hatter’s disease/Erethism
Best antidote for mercurial poisoning
Na formaldehyde sulfoxylate
Water soluble analog BAL
For all types of Hg poisoning
DMSA (Succimer) (dimercapto succinic acid)
Elemental Hg
Penicillamine (Cuprimine®)
Inorg Hg salts only!
BAL
Toxicity for Boric acid
Boiled Lobster appearance
(reddish-orange skin)
Toxicity of Al
Shaver’s disease/Bauxite pneumoconiosis (inhalation),
Alzheimer’s disease in elderly (neurotoxic),
Constipation (ala-tae)
Toxicity of Si
Silicosis - TB like *pneumonoultramicroscopicsilicovolcanoconiosis
Tx of Silicosis
Alumina - forms coat with silica particles
Toxicity of Pb
Plumbism/Saturnism - wrist drop/foot drop
Tx of Plumbism/Saturnism
Ca EDTA/Ca Versenate
Toxicity of Zn
Granuloma in skin & lungs - BANNED!
Acute of P
Garlic odor breath, luminous vomitus, severe GI irritation
Chronic of P
Bony necrosis esp. in mandible (“Phossy Jaw”)
Tx of acute and chronic of P
Cupric sulfate, Ceric sulfate
Acute of As
Aldrich-mee’s, Garlic odor breath, luminous vomitus, severe GI irritation (bloody diarrhea)
Chronic of As
Arsenicosis, Cancer
Tx of acute and chronic of As
BAL/Dimercaprol
What element that can have blue black gums, black stools
Bi
Tx of blue black gums
BAL
Toxicity is green tongue
Vanadium
Hypersensitivity reactions
Angioedema, bronchospasm, anaphylaxis
Deficiency of Selenium
Keshan disease
Toxicity of Selenium
Contact dermatitis
Cr can cause
Hyperglycemia (DM like)
Dental (enamel mottling) & skeletal fluorosis
Flourine
Treatment of Fluorosis
Ca gluconate
Syndrome of Br
Brominism
Treatment of Brominism
Na/NH4Cl
Deficiency of Iodine
Simple/Colloid Goiter
Toxicity of Iodine
Iodism (acute)
Hypothyroidism (chronic)
Treatment of I
Starch solution, NaCl, Na thiosulfate
Parkinson-like (tremors)
Mn