Inner ear Flashcards
What are acquired degenerative diseases of the inner ear?
- Presbycusis
- Meniere’s disease
What are infective causes of inner ear disease?
- Labrynthitis
- Spread from otitis media/cholesteatoma
- Other infections - e.g. mumps
What are vascular causes of inner ear disease?
- Occlusion
- Vasculitis
What are traumatic causes of inner ear disease?
- Acoustic - acute/chronic
- Direct/labyrinthine concussion
- Temporal bone fracture
- Round/oval window rupture
- Drug toxicity
- Surgical
What are metabolic causes of inner ear disease?
- Diabetes mellitus
- Thyroid disease
What is presbycusis?
A degenerative disorder - used to be described as old age hearing loss in both ears. It is characterised by gradual hearing loss, with or without tinnitus
What is the pathophysiological process behind presbycusis?
It can be due to the loss of outer hair cells (sensory), loss of the ganglion cells (neural), strial atrophy (metabolic) or it can be a mixed picture
How would you treat presbycusis?
Hearing aid
What is the typical characteristic of hearing loss caused by presbycusis?
Struggling to hear in places where there is increased background noise
What is labrynthitis?
Acute vestibular failure/Vestibular Neuronitis
Acute inflammation of the inner ear that usually follows a simple URTI
Wht can cause labrynthitis?
- URTI
- Middle ear infection
- Intracranial sepsis
What are features of labyrinthitis?
Sudden attck of unilateral vertigo, accompanied by vomiting
What signs can present in labrynthitis?
- Nystagmus away from affected side
- Hearing loss
Which way will nystagmus go in someone with labrythitis?
Away from affected side - https://www.youtube.com/watch?v=yo-zA1CuKUI
How would you manage someone with suspected labrynthitis?
- Bed Rest
- Vestiular sedatives - Bucastem, cyclizine
How long does it take labrynthitis to resolve?
1-2 days, can take several weeks to fully resolve - residual imbalance with rapid movements for following months
What is a severe complication of labrynthitis?
Total vestibular destruction
What are examples of medications that are ototoxic?
- Gentamicin
- Diuretics
- Malarial drugs
- Co-trimoxazole
- Metranidazole
What is Miniere’s Disease?
A disorder of the inner ear that is characterized by episodes of feeling like the world is spinning (vertigo), ringing in the ears (tinnitus), hearing loss, and a fullness in the ear
What is thought to be the cause of miniere’s disease?
Distention of the membranous labyrinth/endolymphatic space. This is thought to cause small tears in Reissner’s membrane, leading to mixture of endo and periplymph
What are the features of miniere’s disease?
Attacks of the following triad triad of symptoms:
- Tinitus
- Hearling loss
- Vertigo
Also includes:
- Nausea and vomiting
- Feeling of fullness in the ear
How long can miniere’s attacks last?
Acute spinning vertigo for 30 minutes to 4 hours
What type of hearing loss occurs in miniere’s disease?
Sensorineural hearing loss
What features may precede attacks in Miniere’s disease?
- Tinnitus
- Feeling of fullness in the ear
What happens over time in menieres disease?
Attacks of vertigo and tinnitus become permanent
How would you investigate someone with suspected meniere’s disease?
- Clinical history
- Electrocochleography
- Endolymphatic space MRI
- Exclude other causes of vertigo
What are peripheral causes of vertigo?
- Meniere’s disease
- BPPV
- Labyrinthitis/Vestibular Failure
- Cholesteatoma
- Middle ear disease
- Drugs
- Vascular insufficiency
- Post ear-surgery/trauma
What are central causes of vertigo?
- Acoustic neuroma
- Vestibular neuronitis
- MS
- Head Injury
- Inner ear syphillis
- Migraine
- Vascular occlusion
- Epilepsy
How would you manage meniere’s disease acutely?
Vestibular sedatives - bucastem, chlortalidone
How would you manage meniere’s disease in the long-term?
- Betahistine
- Diuretics
- Avoid caffeine and salt
-
Consider destructive interventions
- Intratympanic gentamicin
- Vestibular nerve section
- Labrynthectomy
What is benign paroxysmal positional vertigo?
A disease which is characterised by episodic veritgo that occurs when the head is moved in certain directions
What is thought to be the cause of BPPV?
Dislodged otoliths settling in the posterior semi-circular canal, and with certain movements this causes irritation of the sensory epithelium