Innate Immune System Flashcards

1
Q

TLR1:TLR2

A

Lipopolypeptides

GPI

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2
Q

TLR2:TLR6

A

Lipoteichoic Acid

Zymosan

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3
Q

TLR3

A

Double Stranded Viral RNA

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4
Q

TLR4:TLR4

A

Lipopolysaccharide (Gram Neg)

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5
Q

TLR5

A

Flagellin

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6
Q

TLR7

A

Single Stranded Viral RNA

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7
Q

TLR8

A

Single Stranded Viral RNA

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8
Q

TLR9

A

Unmethylated CpG rich DNA

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9
Q

IL-1

A

Fever, Production of IL-6

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10
Q

IL-6

A

Fever, Acute-Phase Protein Production

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11
Q

TNF-alpha

A

Fever, Shock

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12
Q

IL’s causing fever

A

IL-1, IL-6, TNF-a

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13
Q

IL-10

A

Anti-Inflammatory

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14
Q

TGF-Beta

A

Anti-Inflammatory

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15
Q

Anti-Inflammatory IL’s

A

IL-10, TGF-B

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16
Q

Interferon-y

A

Activation of Macrophages

17
Q

IFN-a

A

anti-viral state

18
Q

IFN-B

A

Anti-viral state

19
Q

Anti-viral state IFNs

A

IFN-a, IFN-B