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Immunology Qbank > Inmuno > Flashcards

Inmuno Flashcards

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1
Q

Vacunas para pacientes esplenectomizados

A

Neumococo
Hib
Meningococo

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2
Q

Hypoplastic thymus (2)

A

DiGeorge sx

SCID

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3
Q

Toll-like receptors

Recognize ? Activate ?

A

Recognize pathogen-associated molecular patterns and activate NF-kB

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4
Q

Examples of PAMPs (3)

A

LPS
Flagellin
Nucleic acids

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5
Q

C3 deficiency increase susceptibility to? (3)

Remove immune complex

A

Neisseria meningitidis
Strepto pneumoniae
Haemophilus influenzae

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6
Q

Leukocyte adhesion deficiency

AR

A 
CD18 beta-2 integrin 
Extreme neutrophilia 
Absent pus 
Impaired wound healing 
Delayed separation umbilical cord
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7
Q

Cells responsible for the pathology in typical pneumonia

A

Neutrophils

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8
Q

Cells responsible for the pathology in atypical pneumonia

A

Macrophages

T lymphocytes

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9
Q

X-linked hyper IgM syndrome

A

deficiency 👉 CD40 L

Recurrent sinopulmonary infections
Opportunistic infections. P jirovecii

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10
Q

Ac predominante posterior a admin de vacuna (polisacarido mas adjuvante no proteinaceo)

A

IgM
Ag polisacárido no activan linf T-helper ya que estos sólo reconocen péptidos y se requiere de activación de linf T para B-cell isotype switch

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11
Q

Marker for drug induced lupus

A

Antihistone ab

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12
Q

Marker for drug induced lupus

A

Antihistone ab

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13
Q

Drugs that can induce LES

A

Hydralazine
Isoniazid
Procainamide

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14
Q

Normal CD8, B cells

Low CD4

A

MHC II deficiency

Severe combined immunodeficiency

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15
Q

Wiskott-Aldrich syndrome

A

High: IgE, IgA

Low to normal: IgG, IgM

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16
Q

Wiskott Aldrich syndrome
Triad ?
Prone to developing ?

A

Thrombocytopenia, Immunodeficiency, Eczema

Prone to non-Hodgkin lymphoma

17
Q

LES (4/11)

A 
Malar rash
Discoid rash
Photosensitivity 
Oral ulcers 
Arthritis 
Serositis 
Renal, neuro, hemato, immunologic disorder 
ANA
18
Q

SLE vasculitis and rash

A

Immune complex deposition in small diameter vessels followed by 👉 complement mediated lysis

19
Q

Preformed mast cell granules

A

Histamine
Heparin
Eosinophil-chemotactic factor-A

20
Q

Intracellular organisms require

A

TH1 responses

Immunology Qbank (1 decks)

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