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inmunologia > inmunidad ante bacterias > Flashcards

inmunidad ante bacterias Flashcards

1
Q

defensa no especifica contra bacterias extracelulares

intersticio y epitelio

A
  • peptidos antimicrobianos
  • barreras epiteliales ( lisis, inflamacion, fagocitosis)
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2
Q

dedenda e specifica contra bacterias extracelulares

A

innata: complementos, fagocitosis, inflamacion
adaptativa: anticuerpos , neutralizan y opsonizan

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3
Q

inflamacion mediada por TLR

A
  • TLR4: LPS
  • TLR5: flagelina
  • TLR9: ADN bacteriano

MAPK, NFK beta(transcripsion genes)

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4
Q

funcion de los superantigenos

A

activan muchos linfocitos T, provocando la liberacion de muchas citocinas, que llevan a una inflamacion sistematica

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5
Q

evasion inmunitaria bacterias extracelulares

A
  • variacion antigenica
  • inh act del complemento
  • resiste fagocitosis
  • captan ROS
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6
Q

evasionsistema inmune intracelular

A
  • inhi formacion fagolisosoma
  • inactiva ROs y RNS
  • rompe membrana fagosoma
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7
Q

inmunidad innat bacterias intracelulalres

citoplasma, vesiculas

A
  • PMN
  • Macrofagos
  • NK
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8
Q

inmunidad adaptativa bacterias intracelulares

A
  • lisis cel infectada
    (Linf T CD8)
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9
Q

diferencias TH1 y Th2

A

TH1: activa macrofago
TH2: inhibe al macrofago

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10
Q

Cb3 + bacteria

A

opsoniza, favoreciendo fagocitosis

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11
Q

funcion INF gamma y CD40

A

activa macrofagos

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12
Q

funcion FAS y TNF beta

A

apoptosis macrofago

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13
Q

funciones IL-2

A

proliferacion cel T

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14
Q

funciones IL-3 , GM- CFS

A

proliferacion macrofagos medula osea

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15
Q

funciones Lt + TNF alfa

A

extravasacion endotelial de macrofago

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16
Q

funciones MFC

A

acumula macrofagos en infecciones

inmunologia (13 decks)

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