Inherited Predisposition to Cancer Flashcards
1
Q
Retinoblastoma
A
RB
2
Q
Li-Fraumeni syndrome (various
tumors)
A
TP53
3
Q
Melanoma
A
CDKN2A
4
Q
Familial adenomatous polyposis/colon
cancer
A
APC
5
Q
Neurofibromatosis 1 and 2
A
NF1, NF2
6
Q
Breast and ovarian tumors
A
BRCA1, BRCA2
7
Q
Multiple endocrine neoplasia 1 and 2
A
MEN1, RET
8
Q
Hereditary nonpolyposis colon cancer
A
MSH2, MLH1, MSH6
9
Q
Nevoid basal cell carcinoma syndrome
A
PTCH1
10
Q
Xeroderma pigmentosum
A
Diverse genes involved in
nucleotide excision repair
11
Q
Ataxia-telangiectasia
A
ATM
12
Q
Bloom syndrome
A
BLM
13
Q
Fanconi anemia
A
Diverse genes involved in
repair of DNA cross-links
14
Q
RB
A
Retinoblastoma
15
Q
TP53
A
Li-Fraumeni syndrome (various
tumors)
