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pathology > Inherited Predisposition to Cancer > Flashcards

Inherited Predisposition to Cancer Flashcards

1
Q

Retinoblastoma

A

RB

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2
Q

Li-Fraumeni syndrome (various
tumors)

A

TP53

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3
Q

Melanoma

A

CDKN2A

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4
Q

Familial adenomatous polyposis/colon
cancer

A

APC

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5
Q

Neurofibromatosis 1 and 2

A

NF1, NF2

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6
Q

Breast and ovarian tumors

A

BRCA1, BRCA2

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7
Q

Multiple endocrine neoplasia 1 and 2

A

MEN1, RET

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8
Q

Hereditary nonpolyposis colon cancer

A

MSH2, MLH1, MSH6

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9
Q

Nevoid basal cell carcinoma syndrome

A

PTCH1

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10
Q

Xeroderma pigmentosum

A

Diverse genes involved in
nucleotide excision repair

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11
Q

Ataxia-telangiectasia

A

ATM

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12
Q

Bloom syndrome

A

BLM

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13
Q

Fanconi anemia

A

Diverse genes involved in
repair of DNA cross-links

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14
Q

RB

A

Retinoblastoma

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1
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15
Q

TP53

A

Li-Fraumeni syndrome (various
tumors)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

CDKN2A

17
Q

APC

A

Familial adenomatous polyposis/colon
cancer

18
Q

NF1, NF2

A

Neurofibromatosis 1 and 2

19
Q

BRCA1, BRCA2

A

Breast and ovarian tumors

20
Q

MEN1, RET

A

Multiple endocrine neoplasia 1 and 2

21
Q

MSH2, MLH1, MSH6

A

Hereditary nonpolyposis colon cancer

22
Q

PTCH1

A

Nevoid basal cell carcinoma syndrome

23
Q

Diverse genes involved in
nucleotide excision repair

A

Xeroderma pigmentosum

24
Q

ATM

A

Ataxia-telangiectasia

25
Q

BLM

A

Bloom syndrome

26
Q

Diverse genes involved in
repair of DNA cross-links

A

Fanconi anemia

pathology (5 decks)

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