Inherited change (complete) Flashcards

1
Q

What is inheritance?

A

The process by which genetic information is passed from parents to offspring.

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2
Q

What is a gene?

A

A segment of DNA that contains the instructions for building a specific protein.

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3
Q

What are alleles?

A

Different versions of a gene that can exist at a specific locus on a chromosome.

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4
Q

What is the genotype?

A

The genetic constitution of an individual, represented by the alleles they possess.

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5
Q

What is the phenotype?

A

The observable physical or biochemical characteristics of an organism, determined by its genotype and/or environmental factors.

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6
Q

What is a homozygous genotype?

A

A genotype consisting of two identical alleles for a particular gene. (both dominant/both recessive)

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7
Q

What is a heterozygous genotype?

A

A genotype consisting of two different alleles for a particular gene. (dominant and recessive)

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8
Q

What is a dominant allele?

A

An allele that expresses its phenotype even when only one copy is present in a heterozygous individual.

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9
Q

What is a recessive allele?

A

An allele that only expresses its phenotype when two copies are present in a homozygous individual.
Is not expressed in phenotype if only one copy present (heterozygous)

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10
Q

True or False: All mutations are harmful, why?

A

False - some can provide protection against certain environmental changes/factors like diseases or climate changes.

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11
Q

What is a gene mutation vs a chromosomal mutation?

A

A change in the nucleotide sequence of DNA that occurs randomly.

A mutation that affects the structure or number of chromosomes.

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12
Q

What does the term ‘monohybrid cross’ refer to?

A

A genetic cross that involves one trait with two alleles.

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13
Q

What is a dihybrid cross?

A

A genetic cross that involves two traits, each with two alleles.

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14
Q

What is the law of segregation?

A

The principle that during gamete formation, the alleles for a trait separate so that each gamete carries only one allele for each gene.

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15
Q

What is the law of independent assortment?

A

The principle that alleles for different traits are distributed to gametes independently of one another.

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16
Q

When does Codominance occur?

A

Codominance occurs when both alleles are fully expressed in the phenotype.

17
Q

What is incomplete dominance?

A

A form of inheritance in which the phenotype of a heterozygote is intermediate between those of the two homozygotes.
The dominant allele doesn’t fully mask the expression of the recessive allele, so both are expressed.

18
Q

What is polygenic inheritance?

A

Inheritance of a trait that is controlled by multiple genes, resulting in a range of phenotypes.

19
Q

What are sex-linked traits?

A

Traits that are associated with genes located on sex chromosomes. (usually the X chromosome)

20
Q

What is the purpose of a pedigree analysis?

A

A method used to understand the inheritance of genetic traits from parents to offspring, and assess the likelihood of genetic disorders in offspring.

21
Q

What is genetic drift?

A

A mechanism of evolution that involves random changes in allele frequencies in a population, due to a random selection of certain genes.
Occurs when the allele itself is not responsible for the change in its frequency.

22
Q

What is natural selection?

A

The process by which individuals with favorable traits are more likely to survive and reproduce, passing on their favourable alleles to their offspring.

23
Q

What is gene flow?

A

The transfer of genetic variation from one population to another through migration/The exchange of alleles between two or more populations.

24
Q

What is genetic engineering?

A

The direct manipulation of an organism’s genes using biotechnology.

25
What is a transgenic organism?
An organism that has been genetically modified to contain a gene from another species.
26
What is gene therapy?
A technique that uses genes to treat or prevent disease.
27
What is linkage in genetics?
The tendency of genes located close together on a chromosome to be inherited together.
28
What is the significance of the Hardy-Weinberg principle?
It provides a mathematical model to study genetic variation in a population under certain conditions.
29
What are the Hardy-Weinberg equilibrium conditions?
Large population size, no mutations, no migration, random mating, and no natural selection.
30
What does 'p' represent in the Hardy-Weinberg equation?
The frequency of the dominant allele in a population.
31
What does 'q' represent in the Hardy-Weinberg equation?
The frequency of the recessive allele in a population.
32
What is the formula for the Hardy-Weinberg principle?
p² + 2pq + q² = 1, where p² is the frequency of homozygous dominant, 2pq is the frequency of heterozygous, and q² is the frequency of homozygous recessive genotypes.
33
Define a chromosome.
- A condensed form of DNA.
34
What is a locus?
- A position of a gene on a particular DNA molecule.
35
Name the different types of chromosomal mutation.
- Polyploidy - Non-disjunction
36
Name the different types of gene mutation.
- Substitution - Deletion - Addition - Inversion
37
38
Define dihybrid inheritance
the inheritance of two characters determined by two difference genes located on different chromosomes.
39
Define epistasis
- When the allele of one gene effects or masks the expression of another in the phenotype.