Inheritance of genes Flashcards

1
Q

In which phase of the cell cycle is genetic information replicated?

A

S

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2
Q

What is the reason for Mitosis?

A

Growth and maintenance of somatic cells

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3
Q

What is the main role of Meiosis?

A

To cause genetic diversity

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4
Q

How can genetic diversity be achieved?

A

Independent assortment of chromosomes

Crossing over

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5
Q

Define genotype

A

The genetic make-up of an individual (either as a whole or one specific genetic locus)

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6
Q

Define phenotype

A

All observable characteristics of an individual or the expressed trait as a result of the genetic make-up of one (or more) specific genetic locus (loci).

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7
Q

How can environmental factors effect the genotype and phenotype?

A

Can directly effect the phenotype

Can effect the genotype and consequently the phenotype

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8
Q

What environmental factors can effect the genotype and phenotype?

A
Radiation
Mutagens
Chemicals that can affect cell growth
Diet
Life-style
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9
Q

What is a gene?

A

A unit of heredity; a length of DNA on a chromosome that contains the code for a protein

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10
Q

What is an allele?

A

An alternative form of a gene; each individual has two alleles for every gene, which can either be the same or different.

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11
Q

What is the pattern for Autosomal dominant inheritance?

A

Usually someone affected in every generation

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12
Q

What is the pattern for Autosomal recessive inheritance?

A

Two heterozygotes –> 25% child affected

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13
Q

What is Autosomal inheritance?

A

When the gene in question is located on an autosome

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14
Q

What is sex linked inheritance?

A

When the gene in question is located on a sex chromosome

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15
Q

Give 2 examples of X linked recessive inherited disorders?

A

Duchenne muscular dystrophy

Haemophillia

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16
Q

Define dominance

A
  • A phenotypic trait is dominant when it occurs in both homo and heterozygotes.
17
Q

Define recessive

A

A phenotypic trait is recessive when it occurs only in homozygotes.

18
Q

Define co dominance

A

When both alleles are expressed in the phenotype of heterozygotes

19
Q

Define complimentation

A

More than one gene is responsible for phenotype

20
Q

What does it mean when 2 genes are linked?

A

The genes are close together on the same chromosome

21
Q

How can 2 linked genes be separated during meiosis?

A

Crossing over and recombination

22
Q

What is a genetic map?

A

The arrangement and distance between genes on a chromosome deduced from studies of recombination.

23
Q

What increases the accuracy of mapping?

A

When the genes are close together

24
Q

How can you tell how close to each other 2 loci are?

A

By the frequency of recombination between the 2 loci