Inheritance Flashcards
What is a gene?
A length of DNA which codes for one polypeptide
What is an allele?
Alternative forms of a gene occupying a similar position/locus on homologous chromosomes
What is meant by a:
a) genotype
b) phenotype
a) The combination of alleles found in an individual
b) The appearance of an organism, determined by the genotype
What is the difference between a dominant allele and a recessive allele?
› A dominant allele is always expressed in the phenotype
› A recessive allele is only expressed in the phenotype in the absence of a dominant allele
What is Mendel’s first law?
The characteristics of an organism are determined by alleles which occur in pairs. Only one member of each pair of alleles can be represented in a single gamete
What is a test cross used for? And how are they carried out?
› Used to find out whether an organism showing a dominant characteristic is heterozygous or homozygous
› By crossing the organism with homozygous recessive
› If homozygous recessive offspring are produced the original organism would have to be heterozygous
What is co-dominance?
When the heterozygous organism expresses both characteristics individually (e.g. chickens with black feathers and white feathers producing speckled offspring)
What is incomplete dominance?
When the heterozygous organism expresses a mixture of both characteristics (e.g. red flowers and white flowers giving rise to pink flowers)
What is the typical ratio expected in a dihybrid cross?
9:3:3:1
What is linkage?
› When two alleles are on the same chromosome
› Without crossing over, only two types of gametes can be produced
› Crossing over allows for a small about of recombinant gametes to be produced
What is the null hypothesis is the χ^2 test?
There is no significant difference between the observed and expected results of a cross
What number of degrees of freedom is used when carrying out a χ^2 test?
One less than the number of classes of data
What does the value obtained for χ^2 mean?
› If lower than the value in the table (the critical value), the null hypothesis is accepted, as there is sufficient evidence that the difference is due to chance
› If higher than the critical value, the null hypothesis is rejected, as there is insufficient evidence that the difference is due to chance