Inheritance Flashcards
Meiosis and Mitosis leads to what type of cells being formed?
Meiosis - non-identical
Mitosis - identical
Human cells contain how many chromosomes in their nucleus?
What about gametes
23 pairs.
Gametes have 23 individuals chromosomes in their nucleus - single and not paired.
Remember gametes are the reproductive cells of animals:
- MALES - Sperm
- FEMALES - Eggs
What type of reproduction produces gametes?
Meiosis. (produces non-identical cells, so every sperm cell and every egg cell is different).
What happens during mitosis?
1 cells is copied into two identical cells.
2 examples of where meiosis occurs:
- In flowering plants, to produce the gametes egg and pollen.
- In animals to produce the gametes sperm and egg.
What is sexual reproduction?
Reproduction that involves the fusion of male and female gametes (fertilisation).
True or false, during sexual reproduction there is a mixing of genetic information which leads to variety in the offspring?
True - this is because every gamete is different.
In asexual reproduction is there a mixing of genetic information?
No. Asexual reproduction only involves one parent (no fusion of gametes involved) - so there is no mixing of genetic information.
This means all the offspring are genetically identical aka clones.
NO VARIATION
Asexual reproduction involves:
While sexual reproduction involves?
ASEXUAL - Mitosis
SEXUAL - Meiosis
Meiosis versus Mitosis
- Meiosis - produces non identical offspring while mitosis produces identical offspring.
- After mitosis offspring have 46 chromosomes, after meiosis offspring have 23 chromosomes.
- Mitosis is involved in asexual reproduction and meiosis occurs during sexual reproduction.
- Mitosis produces 2 offspring but meiosis produces 4 offspring.
- They both result in the production of new offspring.
- They both include cell division.
- In both, DNA doubles.
Asexual Reproduction versus Sexual reproduction:
sims and diffs
- Asexual involves one single parent while sexual reproduction involves more than one parent - a male and female gamete.
- Asexual reproduction - no mixing of genetic info, while sexual there is.
- Asexual reproduction - offspring are genetically identical, while sexual, offspring are not (so there is variation)
- They both result in the production of offspring
Where does meiosis take place?
Only in reproductive organs.
Males - The testes
Females - The ovaries
Meiosis produces how many cells while mitosis produces how many cells?
4 - meiosis
2 - mitosis
Describe the process of cell division by meiosis to form gametes:
- In the cell in the reproductive organ, genetic information of the cell is copied within it.
- The cell now divides twice to form 4 gametes.
- In each gamete there is a single set of chromosomes.
- So each gamete is genetically different from each other.
- At fertilisation the gametes fuse to restore the number of chromosomes
What happens after gametes have been formed by meiosis?
- Male and female gametes join at fertilisation to restore the normal number of chromosomes.
- This new cell is called a zygote which divides by mitosis and the number cells increases to form a ball of cells.
- This ball of cells is called an embryo.
- The cells of an embryo are all genetically identical to one another.
- As the embryo develops the cells differentiate.
Advantages of sexual reproduction:
- SR produces variation in the offspring
- So if the environment changes variation gives a survival advantage by natural selection for the offspring with the advantageous characteristics.
- Natural selection can be sped up by humans in selective breeding to increase food production.
- Less time and energy efficient because do need to find a mate so is slower than asexual reproduction
Advantages of asexual reproduction:
- Only one parent needed
- More time and energy efficient as there is no need to find a parent so is faster than asexual reproduction
- Many identical offspring can be produced when conditions are favourable.
- No variation produced in offspring so if the environment changes, there is no survival advantage amongst offspring - offspring could all die if conditions become unfavourable.
Malarial parasites reproduce asexually when, and sexually when?
- They produce asexually in the human host.
- They produce sexually inside the mosquito.
Fungi reproduce asexually when, and sexually when?
- Both sexually and asexually to produce spores.
Plants produce seeds how?
- Through sexual reproduction
Plants produce sexually when and asexually when?
- Plants produce seeds sexually.
- Plants such as strawberry plants reproduce asexually by runners.
- Plants such as daffodils reproduce asexually via bulb division.
Where is DNA found?
DNA is found on chromosomes.
What is a gene?
A small section of DNA on a chromosome.
What chemical are chromosomes made from?
Chromosomes are made up from the molecule DNA.
What is the role of a gene?
To code for a particular sequence of amino acids which combine together to make a protein.
EG the blood type gene encodes a sequence of amino acids for the protein that determines blood type.
Remember:
Chromosomes are made up of Genes.
Genes are made up of DNA
And so the chromosomes can be said to be made from the molecule DNA.
What does DNA (Deoxyribonucleic acid) do?
DNA determines our inherited features.
Draw and label a diagram of DNA
What is meant by a genome?
The entire set of genetic material of an organism.
FOR EXAMPLE:
- The human genome is the entire genetic material that makes a human.
Describe the benefits of scientists studying the human genome (why is this important?).
3 reasons:
-** It allows for scientists to search for genes linked to different types of diseases.**
- It allows for us to understand and know how to treat inherited disorders.
- we can use the understanding of the human genome to trace human migration patterns from the past, allowing us to learn about our ancestry.
Describe the structure of DNA:
- A polymer consisting of two strands made from nucleotides, which each wrap around each other to form a double helix.
- These DNA strands are made up of monomers called nucleotides
- Nucleotides are made up of the phosphate group, sugar molecule and a base.
Draw and label the diagram of a nucleotide.
Must have:
- Phosphate group (circle)
- Sugar molecule (pentagon)
- Nitrogenous Base (rectangle)
INFO
- In DNA, the phosphate group, and the sugar molecule NEVER change, but bases do.
How many DNA bases are there?
4
A (adenine)
C (cytosine)
G (guanine)
T (thymine)
True or false, DNA strands are complementary?
True. The same bases always pair on the opposite strand.
C G
T A
TRUE OR FALSE?
The order of bases in a gene determines the order of amino acids in a protein, and thus the protein’s shape and therefore its function,
TRUE.
What are proteins?
Polymers of amino acids.
(most proteins contain hundreds of amino acids joined together, but there are only 20 different amino acids in humans)
The specific order of the amino acid determines what…. which determines what….
The specific order of the amino acid determines the shape of the protein which determines the protein’s function.
What is the order of amino acids in a protein determined by?
A gene codes for a particular sequence of amino acids which are put together to make a specific protein.
THAT SEQUENCE OF AMINO ACIDS
The sequence of amino acids in a protein is determined by the sequence of bases in the gene for that protein.
How do cells, at which the DNA is enclosed in read the DNA to know which amino acid to make?
- Each amino acid is coded for by a sequence of three bases.
- The cell at which the DNA is enclosed in reads the DNA sequence in triplets of bases.
- So each triplet codes/tells the cells to make 1 amino acid.
So if the arrangement of the bases was in a different order, a different amino acid would be created.
^^a chain of amino acids is known as a polypeptide.
Describe the process of protein synthesis.
Stage 1: Transcription
- The base sequence of the gene is copied into a complementary template molecule called mRNA.
- mRNA is a single stranded molecule and is used instead of DNA as DNA is too large to move out of the nucleus into the cytoplasm.
- So mRNA moves into the cytoplasm.
(Remember DNA is double stranded).
Stage 2: Translation
- mRNA molecule attaches to the ribosome in the cytoplasm.
- Amino acids are now brought on carrier molecules called tRNA to the ribosome.
- The ribosome reads the
triplets of bases on the mRNA and uses this to join the correct amino acids in the correct order. - This forms a protein chain (polypeptide), and once this is complete it folds into its unique shape which enables it to do its job.
Mutation:
A random change in the sequence of bases in DNA (random change to a gene)
Mutations occur continuously. Most do not alter the protein, or they only alter the protein slightly so that its appearance and function is not changed.
True or false, mutations are continuous and random?
True - mutations happen all the time and they are random.
A change to a sequence of bases may affect the sequence of amino acids the base triplets codes for.
This may affect the protein formed.
However in some cases, a change to a base in a triplet has no effect on the overall structure of the polypeptide, suggest why.
Different bases may still code for that same amino acid.
This is why most mutations have no effect on the structure of a protein and its function.
Describe the consequences that may occur when the base of a gene coding for an enzyme changes.
A few mutations code for an altered protein with a different shape.
(base triplet changes, amino acid coded for changes so protein shape is wrong).
- An enzyme may no longer fit the substrate binding site or a structural protein may lose its strength.
DNA has non-coding parts, and coding parts, true or false?
True, the non-coding parts switch genes on and off (they tell genes when to produce proteins).
How can mutations in the non-coding parts have negative effects?
- These mutations may affect how genes can be switched on or off.
- A gene may be turned on when it should be turned off.
- So the cell will produce a protein that it is not meant to have at that time.
- This may result in uncontrolled mitosis, leading to cancer.
True or false, most characteristics are controlled by many genes acting together?
True
What is an allele?
A different version of a gene - 1 allele is inherited from each parent.
An allele is a variant of a gene - it occupies a chromosome and remember each chromosome is inherited from each parent, which is why we have 2 versions of that gene.
- Look at your notes.
What is meant by the genotype?
A combination of alleles.
So like Cc will be a genotype, or pp will be a genotype.