Inheritance Flashcards
DNA polymerase
catalyzes the elongation of new DNA at a replication fork, can only add nucleotides at the 3’ end
nucleoside triphosphate
the product of each new nucleotide that is adding to a growing DNA strand
What direction can a new DNA strand elongate in?
5’ to 3’ only
leading strand
DNA polymerase can synthesize commplementary stand continuously
lagging strand
synthesized as a series of segments called Okazaki fragments, which are joined together by DNA ligase
primase
enzyme that can start an RNA chain from scratch
helicase
untwists the double helix and separate the template DNA strands at the replication fork
topoisomerase
corrects owverwinding ahead of replication forks by breaking, swiveling, and rejoining DNA strands
DNA pol III
continuously synthesizes the leading strand and elongates Okazaki fragments
DNA Pol I
removes primer from the 5’ ends of the leading strand and Okazaki fragments, replacing primer with DNA and adding to adjacent 3’ ends
DNA Ligase
joins 3’ ends of the DNA that replaces the primer to the rest of the leading strand and also joins the lagging strand of fragments
telomeres
eukaryotic chromosomal DNA molecules have those at the end of their nucleotide sequences; these postpone the erosion of genes near the end of DNA molecules
telomerase
catalyses the lengthening of telomeres in germ cells